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MRX-2843, also known as UNC2371, is a potent and orally active MERTK and FLT3 inhibitor. MRX-2843 overcomes...
MRK-016 is a selective α5 subunit-containing GABAA negative allosteric modulator that has nootropic properties. It...
Mozavaptan free base
CAS#: 137975-06-5 (free base)
Mozavaptan, also known as OPC 31260, is a vasopressin receptor antagonist marketed by Otsuka. In Japan, it was...
Motolimod, also known as VTX-2337, is a small-molecule Toll-like receptor 8 (TLR8) agonist with potential...
UCB-9260 is an orally bioavailable TNF inhibitor. UCB-9260 inhibits TNF signalling by stabilising an asymmetric form...
Estrone sulfate sodium
CAS#: 438-67-5 (sodium)
Estrone sulfate, also known as E1S, E1-S, E1SO4 and estrone 3-sulfate, is a natural, endogenous steroid and an...
SR11237 is a pan retinoid X receptor (RXR) agonist. SR11237 destabilized the RXRα homodimer but promoted formation of...
ALC-0159 is a PEG/lipid conjugate (i.e. PEGylated lipid), specifically, it is the N,N-dimyristylamide of...
CAS#: 1092776-63-0 (HCl salt)
IT1t is a potent and selective CXCR4 antagonist (IC50 = 1.1 nM in calcium mobilization assays). IT1t may be...
CAS#: 188791-09-5 (HCl)
JTE-607, also known as TO-207, is a cytokine production inhibitor potentially for the treatment of systemic...
HaloPROTAC3 is a degrader of HaloTag fusion proteins.
CRANAD-2 is a difluoroboron-derivatized curcumins as near-infrared probe for in vivo detection of amyloid-beta...
CB-6644 is a novel allosteric selective inhibitor of the ruvbl1/2 complex with anti-cancer activity. CB-6644 blocks...
Mavorixafor free base
CAS#: 558447-26-0 (free base)
Mavorixafor, also known as AMD11070, AMD070, X4P-001, is an orally bioavailable and potent CXCR4 inhibitor. AMD11070...
CAS#: 2189684-44-2 (free base)
Lenacapavir, also known as GS-6207, is a HIV-1 capsid inhibitor. Lenacapavir shows anti-HIV activity. Lenacapavir...
BLU-945 is a fourth-generation, potent and highly selective epidermal growth factor receptor tyrosine kinase...
Vaneprim is an antibacterial agent.
CAS#: 2561414-57-9 (HCl)
GNF2133 is a potent and selective DYRK1A inhibitor (IC50 = 6 nM). In vitro, GNF2133 is able to proliferate both...
Icenticaftor, also known as QBW251 is a Cystic Fibrosis Transmembrane Conductance Regulator Potentiator with Clinical...
GLPG2938 is an antagonists of sphingosine-1-phosphate (S1P) receptor for prophylaxis and/or treatment of diseases...
CAS#: 1883545-52-5 (TFA)
MM-102 is a Potent WDR5/MLL interaction inhibitor. The MM-102 compound prevents the interaction between mixed lineage...
MLS1547 is a highly efficacious D2 dopamine receptor (D2R) G protein-biased agonist that does not recruit β-arrestin,...
BAY-8400 is a novel selective inhibitor of DNA-PK. In in vitro studies, BAY-8400 showed synergistic activity of...
CAS#: 1782573-78-7 (2HCl)
MLN-120B is a potent and effective inhibitor of IκB kinase beta subunit (IKKβ) with IC50 value of 20 μM. MLN-120B...
ML-7 is a MLCK inhibitor. ML-7 inhibits smooth muscle myosin light chain kinase (MLCK) with a Ki value of 0.3 µM....