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PT2385 is an orally active, small molecule inhibitor of hypoxia inducible factor (HIF)-2alpha, with potential...
AG-636 is a potent, reversible, selective and orally active dihydroorotate dehydrogenase (DHODH) inhibitor with an...
CAS#: 56974-61-9 (mesylate)
Gabexate is a serine protease inhibitor which is used therapeutically (as gabexate mesilate) in the treatment of...
CRT0273750 is an autotaxin inhibitor. CRT0273750 modulates LPA levels in plasma and is suitable for in vivo studies....
FH535 is a β-catenin pathway inhibitor. FH535 represses pancreatic cancer xenograft growth and angiogenesis. FH535...
Ferrostatin-1 (Fer-1) is a lipophilic antioxidant that effectively blocks ferroptosis, a distinct non-apoptotic form...
Exatecan free base
CAS#: 171335-80-1 (free base)
Exatecan, also known as DX 8951, is a semisynthetic, water-soluble derivative of camptothecin with antineoplastic...
CAS#: 169869-90-3 (mesylate)
Exatecan, also known as DX 8951, is semisynthetic, water-soluble camptothecin derivative with antineoplastic...
Ralmitaront, also known as WHO 11130, RO 6889450 and RG7906, is a neuroleptic.
CAS#: 1957203-01-8 (free base)
YKL-5-124 is a potent and highly selective covalent CDK7 inhibitor which causes arrest at the G1/S transition and...
4-hydroxynonenal is a lipid peroxidation product derived from oxidized ω-6 polyunsaturated fatty acids. 4-hydroxy...
ALW-II-41-27 is a Eph receptor tyrosine kinase inhibitor. pharmacologic inhibition of EPHA2 by the small-molecule...
Fadraciclib free base
CAS#: 1070790-89-4 (free base)
Fadraciclib, also known as CYC065, is an orally bioavailable inhibitor of cyclin dependent kinases 2, 5 and 9...
DC-260126 is a FFA1 (GPR40) antagonist.
A2793 is an inhibitor of TRESK (IC50 value of 6.8 μM for mTRESK). A2793 inhibited TWIK-related acid-sensitive K+...
CAS#: 2365172-42-3 (free base)
DT2216 is a selective B-cell lymphoma extra large (BCL-XL) proteolysis-targeting chimera (PROTAC). DT2216 targets...
CYC116 is an orally bioavailable small molecule multi-kinase inhibitor with antineoplastic activity. Aurora...
SB-334867 free base
CAS#: 792173-99-0 (free base)
SB-334867 is an orexin antagonist. It was the first non-peptide antagonist developed that is selective for the orexin...
TAS-103 HCl salt (BMS-247615)
TAS-103, also known as BMS-247615, is a quinoline derivative that displays antitumor activity in murine and human...
Diflapolin is a potent dual soluble epoxide hydrolase (sEH)/5-lipoxygenase-activating protein (FLAP) inhibitor. It...
CRT0066101 free base
CAS#: 956121-30-5 (free base)
CRT0066101 is a PRKDs inhibitor. CRT0066101 suppressed the proliferation and migration of four bladder cancer cell...
Desidustat is an antianaemic drug candidate.
CAS#: 1995889-48-9 (HCl)
Parsaclisib, also known as INCB050465, is a novel PI3Kδ inhibitor which synergizes with PIM protein kinase...
CPI-637 is a potent and selective CBP/ EP300 bromodomain inhibitor. The biochemical potency of CPI-637 translated...
Etripamil is a calcium channel blocker. Calcium channel blockers (CCB), calcium channel antagonists or calcium...