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CAS#: Rezafungin chloride
Rezafungin is a novel, once-weekly antifungal being developed for the treatment and prevention of serious fungal...
LSZ102 is a potent ERα antagonist and degrader. LSZ102 showed ERα degradation IC50 = 0.2 nM. LSZ102 demonstrated IC50...
VV116, also known as JT001, is an oral drug candidate of nucleoside analog against SARS-CoV-2. VV116 is a deuterated,...
CAS#: 55750-05-5 (HCl)
Caroverine is a nonselective NMDA and AMPA glutamate receptor antagonist, also acting as a class B...
LP-261 is a novel tubulin targeting anticancer agent that binds at the colchicine site on tubulin, inducing G2/M...
GSK215 is a potent, selective, FAK-degrading Proteolysis Targeting Chimera (PROTAC) based on a binder for the VHL E3...
CAS#: 181147-28-4 (HCl)
YCN47284 is an aromatic guanylhydrazone compounds with antimalarial activity. YCN47284 was first reported in WO...
TPX-0131 is a Potent CNS-penetrant, Next-generation Inhibitor of Wild-type ALK and ALK-resistant Mutations. In...
Lomitapide free base
CAS#: 182431-12-5 (free base)
Lomitapide is a MTP inhibitor. Lomitapid is a novel agent for the treatment of homozygous familial...
MRTX1133 is a potent and selective KRAS G12D inhibitor. MRTX1133 targets the KRAS G12D protein in both active and...
LMN75224 is a phosphodiesterase 1 inhibitors useful for treatment of neurological and psychiatric disorder. LMN75224...
LML134 is an orally active and high selective Histamine 3 receptor (H3R) inverse agonist with Kis of 0.3 nM and 12 nM...
CKK-E12 is an ionizable lipid. It is useful for Development of Lipidoid Nanoparticles for siRNA, mRNA, and vaccine...
C12-200 is Potent Branched-Tail Lipid. C12-200 is useful for Development of Lipidoid Nanoparticles for siRNA, mRNA,...
AZD6703 free base
CAS#: 851845-37-9 (free base)
AZD6703 is a potent, selective and reversible orally bioavailable inhibitor of p38 mitogen-activated protein kinase...
FR901464 is a potent spliceosome inhibitor and a potential agent for colorectal cancer in combination therapy.
AZD-2207 is a cannabinoid receptor CB1 antagonist and highly lipophilic compound for the treatment of type 2 diabetes...
Atigliflozin, also known as AVE 2268, is an antihyperglycaemic drug candidate.
LM22B-10 is a TrkB and TrkC agonist. LM22B-10 exhibits neurotrophic activity (EC50 = 200-300 nM). LM22B-10 improves...
CAS#: 201740-84-3 (C13-labeled)
L-LEUCINE-13C6, also known as 13C6-D-Leucine or L-Leucine-1,2,3,4,5,5'-13C6, is a fully 13C labelled D-Leucine.
CAS#: 1263774-59-9 (free)
Delgocitinib, also known as LEO-124249 and JTE052, is a potent and selective JAK inhibitor. JTE-052 reduces skin...
CMP3a is a NEK2 kinase inhibitor. CMP3a efficiently attenuated GBM growth in a mouse model and exhibited a...
LJI308 is a RSK inhibitor. LJI308 overcomes chemoresistance by eliminating cancer stem cells. LJI308 targets the...
CAS#: 2410512-38-6 (free base)
JQKD82, also known as PCK82, is a cell-permeable and selective KDM5 inhibitor (MM.1S cells, IC50 = 0.42 uM). JQKD82...
Ulodesine, also known as BCX4208, is a purine nucleoside phosphorylase (PNP) inhibitor in development as a once-daily...