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HM43239 is an orally active small molecule inhibitor of FLT3 that selectively inhibits not only FLT3 wild type, ITD...
CAS#: 2757470-18-9 (fumarate)
Ensitrelvir, also known as S-217622, is an antiviral drug developed by Shionogi in partnership with Hokkaido...
SM-102 is an ionizable amino lipid that has been used in combination with other lipids in the formation of lipid...
ALC-0315 is a synthetic cationic lipid (or ionizable lipid). It is a colorless oily material, It has attracted...
CAS#: 1610358-53-6 (racemate)
BAY-1251152 racemate, also known as (±)-BAY-1251152, is a racemic mixture of BAY-1251152. BAY-1251152 is a potent and...
GSK4112 is a selective Rev-Erbα agonist (EC50 = 250 nM). GSK4112 enhances recruitment of nuclear receptor...
GSK3i XIII is an ATP-binding site inhibitor of GSK-3.
SGI-7079 is a potent and selective Axl inhibitor with potential anticancer activity. SGI-7079 effectively inhibited...
GSK3039294 is an orally available small molecule inhibitor of serum amyloid P component (SAP) binding to amyloid...
CAS#: 1622848-92-3 (free base)
GSK2982772 is a potent and selective receptor Interacting Protein 1 (RIP1) Kinase Specific Clinical Candidate for...
Deruxtecan, a topoisomerase I inhibitor, is an exatecan derivative (DX-8951 derivative) with a cleavable pepetide...
CAS#: 1224095-99-1 (HCl)
Brilacidin, also known as PMX30063, is an arylamide foldamer designed to replicate the amphiphilic properties of...
ML-SI3 is a chemical compound which acts as an "antagonist" (i.e. channel blocker) of the TRPML family of calcium...
CAS#: 203120-46-1 (octanoate)
Laninamivir Octanoate, also known as CS-8958, is a long acting neuraminidase inhibitor which shows superior...
PFK-158, also known as ACT-PFK-158, is an inhibitor of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatases...
GSK2879552 is an orally available, irreversible, inhibitor of lysine specific demethylase 1 (LSD1), with potential...
GSK2814338, also known as Lp-PLA2 -IN-1, is a Lp-PLA2 inhibitor
CAS#: 2245255-66-5 (TFA)
GSK2807 is a potent and selective, SAM-competitive inhibitor of SMYD3 (Ki = 14 nM). GSK2807 bridges the gap between...
CAS#: 2095432-71-4 (HCl)
GSK269962 is a selective ROCK inhibitor with IC50 values of 1.6 and 6 nM for ROCK-I and ROCK-II, respectively. GSK...
AP-III-a4, also known as ENOblock, is the first, nonsubstrate inhibitor of enolase, blocking cancer cell metastasis...
CB-6644 is a novel allosteric selective inhibitor of the ruvbl1/2 complex with anti-cancer activity. CB-6644 blocks...
CAS#: 2417987-45-0 (active atropisomer)
GDC-6036, also known as RG6330, is an orally bioavailable, highly potent and selective KRAS G12C inhibitor, with a...
GSK2200150A is an antimycobacterial agent against Mycobacterium tuberculosis and Mycobacterium bovis BCG.
ALC-0159 is a PEG/lipid conjugate (i.e. PEGylated lipid), specifically, it is the N,N-dimyristylamide of...
CAS#: 2003234-63-5 (R-isomer)
R-GNE-140 a novel potent lactate dehydrogenase (LDHA) inhibitor with IC50 3nM for LDHA and 5 nM for LDHB. In MIA...