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BO-264

CAT#: 408094
CAS#: 2408648-20-2

BO-264 is a highly potent and orally active transforming acidic coiled-coil 3 (TACC3) inhibitor with an IC50 of 188...

EIDD-2801

CAT#: 555745
CAS#: 2349386-89-4

EIDD-2801 is an orally bioavailable form of a highly potent ribonucleoside analog that inhibits the replication of...

RU-58841

CAT#: 555811
CAS#: 154992-24-2

RU-58841 is a non-steroidal antiandrogen that binds to the androgen receptor. RU 58841 is a Candidate of Choice for...

RA371

CAT#: 408107
CAS#: Unknown

RA371, a derivative of PTP1B-IN-8 (CAS#919091-61-5), is a potent and selective potent protein tyrosine phosphatase-1B...

GNE-3511

CAT#: 522419
CAS#: 1496581-76-0

GNE-3511 is a potent and selective dual leucine zipper kinase (DLK, MAP3K12) inhibitors with activity in...

Sonidegib (LDE-225)

CAT#: 205510
CAS#: 956697-53-3 (free base)

Sonidegib, also known as, erismodegib, LDE225, NVP-LDE225, is an orally bioavailable small-molecule Smoothened (Smo)...

CL2A-SN38 DCA

CAT#: 408080
CAS#: 1279680-68-0 (free base)

CL2A-SN38 is a SN38 derivative with a peptide-linker which can easily react with antibody to form an antibody-drug...

Pibrentasvir

CAT#: 528903
CAS#: 1353900-92-1 (free)

Pibrentasvir, also known as ABT-530, is a protease inhibitor potentially for the treatment of HCV infection.

Semaxanib

CAT#: 205994
CAS#: 204005-46-9 (free base)

Semaxanib, also known as SU5416, is a quinolone derivative with potential antineoplastic activity. Semaxanib...

HS-173

CAT#: 406355
CAS#: 1276110-06-5

HS-173 is a potent PI3Kα inhibitor with potential anticancer activity. HS-173 inhibited the PI3K signaling pathway,...

GW280264X

CAT#: 555806
CAS#: 866924-39-2

GW280264X is an ADAM17 inhibitor.

LQZ-7I

CAT#: 408100
CAS#: 195822-23-2

LQZ-7I is a malarial protease PfSUB1 inhibitor. LQZ-7I showed significantly improved activity and is the focus of...

SB-334867 free base

CAT#: 530968
CAS#: 792173-99-0 (free base)

SB-334867 is an orexin antagonist. It was the first non-peptide antagonist developed that is selective for the orexin...

DUN73423

CAT#: 408104
CAS#: 2414373-42-3

DUN73423 is a RET/KDR-Selective Inhibitor of RETV804M Kinase with IC50 = 7 nM. DUN73423 was listed in ACS Med Chem...

NE 52-QQ57

CAT#: 555805
CAS#: 1401728-56-0

NE52-QQ57 is an orally available GPR4 antagonist with an IC50 of 70 nM. NE 52-QQ57 significantly inhibited the...

Avasimibe

CAT#: 406842
CAS#: 166518-60-1

Avasimibe is an acyl coenzyme A: cholesterol acyltransferase (ACAT) inhibitor. Avasimibe can also reduce the...

LUN09945

CAT#: 408102
CAS#: 2414909-94-5

LUN09945 is a potent RETV804M kinase inhibitor. LUN09945 was first reported by Rebecca Newton et al (Compound 13, in...

RAMB4

CAT#: 408101
CAS#: 145888-79-5

RAMB4, also known as PTP1B-IN-9, is a ubiquitin-proteasome system (UPS)-stressor. RAMB4 selectively reduces the...

PF06447475

CAT#: 406655
CAS#: 1527473-33-1

PF06447475 is a highly potent, selective, brain penetrant, and in vivo active LRRK2 kinase inhibitor. Leucine rich...

GW-870086

CAT#: 530012
CAS#: 827319-43-7

GW-870086 is a glucocorticoid receptor agonist potentially for the treatment of asthma and atopic dermatitis.

Dactinomycin

CAT#: 100220
CAS#: 50-76-0

Dactinomycin (also known generically as Actinomycin D) is the most significant member of actinomycines, which are a...

Pexidartinib HCl

CAT#: 207104
CAS#: 2040295-03-0 (HCl)

Pexidartinib, also know as PLX-3397, is a CSF1R inhibitor with IC50 of 20 nM in development by Plexxikon for the...

SC-26196

CAT#: 555802
CAS#: 218136-59-5

SC-26196 is a D6D inhibitor (IC50 = 0.2 µM in a rat liver microsomal assay) that completely blocks the conversion of...

BC-DXI-843

CAT#: 593189
CAS#: 2421117-98-6

BC-DXI-843 is AIMP2-DX2 inhibitor. It as a promising lead for development of novel therapeutics targeting AIMP2-DX2...

RA-9 UPS inhibitor

CAT#: 408099
CAS#: 919091-63-7

RA-9 is a cell permeable and potent inhibitor of the ubiquitin-proteasome system (UPS). RA-9 Inhibits...