STC-15
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 207203

CAS#: 2648257-56-9

Description: STC-15 is a potent METTL3 inhibitor. STC-15 inhibits METTL3, an RNA methyltransferase implicated in oncology and other diseases. STC-15 has also been shown to inhibit tumor growth through mechanisms involving anti-cancer immune responses such as changes in interferon signaling and synergy with T cell checkpoint blockade. In addition, STC-15 has demonstrated efficacy in leukemia models via mechanisms such as inhibition of leukemia stem cell function.


Chemical Structure

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STC-15
CAS# 2648257-56-9

Theoretical Analysis

MedKoo Cat#: 207203
Name: STC-15
CAS#: 2648257-56-9
Chemical Formula: C24H25N5O2
Exact Mass: 415.20
Molecular Weight: 415.497
Elemental Analysis: C, 69.38; H, 6.07; N, 16.86; O, 7.70

Price and Availability

Size Price Availability Quantity
10mg USD 550 2 Weeks
25mg USD 850 2 Weeks
50mg USD 1250 2 Weeks
100mg USD 1950 2 Weeks
1g USD 6950 2 Weeks
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Synonym: STC-15; STC 15; STC15;

IUPAC/Chemical Name: N-((2-(((cyclobutylmethyl)amino)methyl)-1H-indol-6-yl)methyl)-4-oxo-4H-pyrido[1,2-a]pyrimidine-2-carboxamide

InChi Key: MFQFZLWCFZZHAI-UHFFFAOYSA-N

InChi Code: InChI=1S/C24H25N5O2/c30-23-12-21(28-22-6-1-2-9-29(22)23)24(31)26-14-17-7-8-18-11-19(27-20(18)10-17)15-25-13-16-4-3-5-16/h1-2,6-12,16,25,27H,3-5,13-15H2,(H,26,31)

SMILES Code: O=C1C=C(C(NCC2=CC3=C(C=C(CNCC4CCC4)N3)C=C2)=O)N=C5C=CC=CN15

Appearance: To be determined

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 415.50 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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