TZ3O
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 125226

CAS#: 2218754-19-7

Description: TZ3O (compound TZ30) is an anticholinergic agent with neuroprotective effects.

Chemical Structure

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TZ3O
CAS# 2218754-19-7
Instruction

Theoretical Analysis

MedKoo Cat#: 125226
Name: TZ3O
CAS#: 2218754-19-7
Chemical Formula: C18H13NO4S
Exact Mass: 339.06
Molecular Weight: 339.370
Elemental Analysis: C, 63.71; H, 3.86; N, 4.13; O, 18.86; S, 9.45

Price and Availability

Size Price Availability Quantity
100mg USD 750 2 Weeks
200mg USD 1250 2 Weeks
500mg USD 2650 2 Weeks
1g USD 3850 2 Weeks
2g USD 5950 2 Weeks
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Synonym: TZ3O; TZ3-O; TZ 3-O; TZ-3O; TZ 3O; compound TZ30

IUPAC/Chemical Name: (E)-5-(3-hydroxybenzylidene)-3-(2-oxo-2-phenylethyl)thiazolidine-2,4-dione

InChi Key: XISJGNSKAXXSAO-MHWRWJLKSA-N

InChi Code: InChI=1S/C18H13NO4S/c20-14-8-4-5-12(9-14)10-16-17(22)19(18(23)24-16)11-15(21)13-6-2-1-3-7-13/h1-10,20H,11H2/b16-10+

SMILES Code: O=C(S/C1=C/C2=CC=CC(O)=C2)N(C1=O)CC(C3=CC=CC=C3)=O

Appearance: To be determined

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 339.37 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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Taheri M, Ghafoori H, Sepehri H, Mohammadi A. Neuroprotective Effect of Thiazolidine-2,4-dione Derivatives on Memory Deficits and Neuropathological Symptoms of Dementia on a Scopolamine-Induced Alzheimer's Model in Adult Male Wistar Rats. ACS Chem Neurosci. 2023 Sep 6;14(17):3156-3172. doi: 10.1021/acschemneuro.3c00294. Epub 2023 Aug 10. PMID: 37561907.