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c-Met Products

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406405
SU11606
SU11606 is a potent c-MET inhibitor with potential anticancer activity.
406406
SU11271
SU11271 is a potent c-MET inhibitor with potential anticancer activity.
406114
KRC-108
KRC-108 is a multiple kinase inhibitor. KRC-108 is a potent inhibitor of Ron, Flt3 and TrkA as well …
206080
Savolitinib
featured
Savolitinib, also known as Volitinib, AZD6094 or HMPL-504, is an orally bioavailable inhibitor of th…
200283
Tivantinib
featured
Tivantinib (ARQ-197) is an orally bioavailable small molecule inhibitor of c-Met with potential anti…
202231
PHA-665752
featured
PHA665752 is a potent and selective inhibitor of c-Met/HGF/SF (IC50 values are 9, 68, 200, 1400, 300…
206070
Tepotinib HCl (discontinued)
Tepotinib HCl was discontinued for commercial reason.
525682
MK-2461
featured
MK-2461 is a novel ATP-competitive multitargeted inhibitor of activated c-Met. MK-2461 inhibited in …
201841
MGCD-265-analog
featured
MGCD265-analog, CAS#875337-44-3, is structurally related to MGCD-265 (Glesatinib). MGCD-265-analog i…
205526
Merestinib (LY2801653)
featured
Merestinib, also known as LY2801653, is an orally available, small molecule inhibitor of the proto-o…
201615
JNJ-38877605
featured
JNJ-38877605 is an orally bioavailable, small-molecule receptor tyrosine kinase inhibitor with poten…
201372
Foretinib
featured
Foretinib, also known as XL880 and GSK1363089, is an orally bioavailable small molecule with potenti…
205898
AMG-458
featured
AMG 458 is a potent c-Met inhibitor with Ki of 1 nM ~ 2.0 nM. AMG-458 was found to significantly inh…
204320
AMG-337
featured
AMG 337 is an orally bioavailable inhibitor of the proto-oncogene c-Met with potential antineoplasti…
200185
AMG208
featured
AMG 208 is a selective small-molecule inhibitor of the proto-oncogene c-Met with potential antineopl…
206143
Altiratinib
new
featured
Altiratinib, also known as DCC-270, DP-5164, is an oral, selective and highly potent inhibitor of ME…
201145
Tepotinib (discontinued)
Tepotinib was discontinued for commercial reason.
201950
Amuvatinib
featured
Amuvatinib, also known as MP-470, is an orally bioavailable synthetic carbothioamide with potential …
205889
SAR125844
SAR125844 is a potent and highly selective c-Met inhibitor with potential antineoplastic activity. U…
202221
PF-04217903
featured
PF-04217903 is a MET tyrosine kinase inhibitor, is also a n orally bioavailabe, small-molecule tyros…
205494
Capmatinib
featured
Capmatinib, also known as INCB28060 and INC280, is an orally bioavailable inhibitor of the proto-onc…
201072
Golvatinib
featured
Golvatinib, also known as E7050, is an orally bioavailable dual kinase inhibitor of c-Met (hepatocyt…
200595
Cabozantinib (free base)
featured
Cabozantinib, also known as XL-184 and BMS-907351, is the s-malate salt form of cabozantinib, an or…
200527
BMS-777607
featured
BMS-777607, also known as BMS-817378 and ASLAN-002, a Met tyrosine kinase inhibitor, is an inhibito…
202222
Crizotinib
featured
Crizotinib, also known as PF-02341066, is an orally bioavailable agent belonging to the class of c-m…