Prisotinol dihydrochloride

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 125412

CAS#: 76906-72-4 (2HCl)

Description: Prisotinol is aminoalkyl-5-pyridinol patented by Ciba-Geigy A.-G. for treatment of angina pectoris. Prisotinol was studied in phase II clinical trials as a cardioprotective agent.

Chemical Structure

img
Prisotinol dihydrochloride
CAS# 76906-72-4 (2HCl)
Instruction

Theoretical Analysis

MedKoo Cat#: 125412
Name: Prisotinol dihydrochloride
CAS#: 76906-72-4 (2HCl)
Chemical Formula: C11H20Cl2N2O
Exact Mass: 266.10
Molecular Weight: 267.190
Elemental Analysis: C, 49.45; H, 7.55; Cl, 26.54; N, 10.48; O, 5.99

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Related CAS #: 76906-72-4 (2HCl)   76906-79-1 (free base)  

Synonym: Prisotinol dihydrochloride; HV83YDG8YK; C3LFG625CK; PPP3N7B22F; Prisotinol dihydrochloride, (+)-

IUPAC/Chemical Name: 6-(2-(isopropylamino)propyl)pyridin-3-ol dihydrochloride

InChi Key: WWKMQPRSOJYBNS-UHFFFAOYSA-N

InChi Code: InChI=1S/C11H18N2O.2ClH/c1-8(2)13-9(3)6-10-4-5-11(14)7-12-10;;/h4-5,7-9,13-14H,6H2,1-3H3;2*1H

SMILES Code: Cl.Cl.CC(C)NC(C)CC1=CC=C(O)C=N1

Appearance: To be determined

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 267.19 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

1: Molloy DW, Guyatt GH, Standish T, Willan A, McIlroy W, D'Souza J, Brown G, Mondadori C. Effect of a new nootropic agent, CGS 5649B, on cognition, function, and behavior in dementia. J Gen Intern Med. 1993 Aug;8(8):444-7. doi: 10.1007/BF02599624. PMID: 8410411.

2: Mondadori C, Ducret T, Borkowski J. How long does 'memory consolidation' take? New compounds can improve retention performance, even if administered up to 24 hours after the learning experience. Brain Res. 1991 Jul 26;555(1):107-11. doi: 10.1016/0006-8993(91)90866-t. PMID: 1933323.

3: Nilsson E, Schneider T, Hoffmann E, Schmidt EK. Urinary excretion of CGS 5,649 and its conjugated glucuronide and sulfate in man. Eur J Drug Metab Pharmacokinet. 1991;Spec No 3:201-4. PMID: 1820879