Clindamycin hydrochloride hydrate
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MedKoo CAT#: 471128

CAS#: 58207-19-5 (HCl monohydrate)

Description: Clindamycin HCl hydrate is a ribosomal translocation and protein synthesis inhibitor that displays efficacy against MRSA. It is also occasionally used to treat Plasmodium. It has the same antibacterial spectrum as lincomycin, but the antibacterial activity is four to eight times stronger than that of lincomycin.

Chemical Structure

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Clindamycin hydrochloride hydrate
CAS# 58207-19-5 (HCl monohydrate)
Instruction

Theoretical Analysis

MedKoo Cat#: 471128
Name: Clindamycin hydrochloride hydrate
CAS#: 58207-19-5 (HCl monohydrate)
Chemical Formula: C18H36Cl2N2O6S
Exact Mass: 0.00
Molecular Weight: 479.450
Elemental Analysis: C, 45.09; H, 7.57; Cl, 14.79; N, 5.84; O, 20.02; S, 6.69

Price and Availability

Size Price Availability Quantity
5g USD 280 2 Weeks
10g USD 500 2 Weeks
25g USD 800 2 Weeks
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Related CAS #: 21462-39-5 (HCl)   18323-44-9 (free)   24729-96-2 (phosphate)   58207-19-5 (HCl monohydrate)   25507-04-4 (palmitate HCl)  

Synonym: Clindamycin HCl (H2O); Clindamycin hydrochloride hydrate

IUPAC/Chemical Name: (2S,4R)-N-((1S,2S)-2-chloro-1-((2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(methylthio)tetrahydro-2H-pyran-2-yl)propyl)-1-methyl-4-propylpyrrolidine-2-carboxamide hydrochloride hydrate

InChi Key: KWMXKEGEOADCEQ-WNNJHRBUSA-N

InChi Code: InChI=1S/C18H33ClN2O5S.ClH.H2O/c1-5-6-10-7-11(21(3)8-10)17(25)20-12(9(2)19)16-14(23)13(22)15(24)18(26-16)27-4;;/h9-16,18,22-24H,5-8H2,1-4H3,(H,20,25);1H;1H2/t9-,10+,11-,12+,13-,14+,15+,16+,18+;;/m0../s1

SMILES Code: O.Cl.CCC[C@@H]1C[C@H](N(C)C1)C(=O)N[C@H]([C@H](C)Cl)[C@H]2O[C@H](SC)[C@H](O)[C@@H](O)[C@H]2O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 479.45 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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