MA-0204 sodium

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MedKoo CAT#: 565657

CAS#: 2095128-17-7 (free acid)

Description: MA-0204 is a novel highly potent and selective pparδ modulator


Chemical Structure

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MA-0204 sodium
CAS# 2095128-17-7 (free acid)

Theoretical Analysis

MedKoo Cat#: 565657
Name: MA-0204 sodium
CAS#: 2095128-17-7 (free acid)
Chemical Formula: C25H26F3N2NaO4
Exact Mass: 476.1923
Molecular Weight: 498.478
Elemental Analysis: C, 60.24; H, 5.26; F, 11.43; N, 5.62; Na, 4.61; O, 12.84

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Related CAS #: 2095128-30-4   2095128-17-7 (free acid)    

Synonym: MA-0204; MA 0204; MA0204; MA-0204 sodium;

IUPAC/Chemical Name: sodium (R)-3-methyl-6-(2-((5-methyl-2-(4-(trifluoromethoxy)phenyl)-1H-imidazol-1-yl)methyl)phenoxy)hexanoate

InChi Key: DEMPZEPJIMOVJT-UNTBIKODSA-M

InChi Code: InChI=1S/C25H27F3N2O4.Na/c1-17(14-23(31)32)6-5-13-33-22-8-4-3-7-20(22)16-30-18(2)15-29-24(30)19-9-11-21(12-10-19)34-25(26,27)28;/h3-4,7-12,15,17H,5-6,13-14,16H2,1-2H3,(H,31,32);/q;+1/p-1/t17-;/m1./s1

SMILES Code: O=C([O-])C[C@H](C)CCCOC1=CC=CC=C1CN2C(C)=CN=C2C3=CC=C(OC(F)(F)F)C=C3.[Na+]

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 498.478 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Lagu B, Kluge AF, Tozzo E, Fredenburg R, Bell EL, Goddeeris MM, Dwyer P, Basinski A, Senaiar RS, Jaleel M, Tiwari NK, Panigrahi SK, Krishnamurthy NR, Takahashi T, Patane MA. Selective PPARδ Modulators Improve Mitochondrial Function: Potential Treatment for Duchenne Muscular Dystrophy (DMD). ACS Med Chem Lett. 2018 Jul 31;9(9):935-940. doi: 10.1021/acsmedchemlett.8b00287. eCollection 2018 Sep 13. Erratum in: ACS Med Chem Lett. 2019 Apr 24;10(6):1013. PubMed PMID: 30258544; PubMed Central PMCID: PMC6142063.