CP 74667

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 524816

CAS#: 108461-05-8

Description: CP 74667 is a new fluoroquinolone that has good activity against several gram-positive and gram-negative pathogens.

Chemical Structure

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CP 74667
CAS# 108461-05-8
Instruction

Theoretical Analysis

MedKoo Cat#: 524816
Name: CP 74667
CAS#: 108461-05-8
Chemical Formula: C20H22FN3O3
Exact Mass: 371.16
Molecular Weight: 371.410
Elemental Analysis: C, 64.68; H, 5.97; F, 5.12; N, 11.31; O, 12.92

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: CP 74667; CP74667; CP-74667; UNII-D66A707X1B.

IUPAC/Chemical Name: 3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-7-(8-methyl-3,8-diazabicyclo(3.2.1)oct-3-yl)-4-oxo-

InChi Key: ALRZZABRVIYCNY-BETUJISGSA-N

InChi Code: InChI=1S/C20H22FN3O3/c1-22-12-4-5-13(22)9-23(8-12)18-7-17-14(6-16(18)21)19(25)15(20(26)27)10-24(17)11-2-3-11/h6-7,10-13H,2-5,8-9H2,1H3,(H,26,27)/t12-,13+

SMILES Code: CN1[C@H]2CC[C@@H]1CN(C2)c3cc4N(C=C(C(=O)O)C(=O)c4cc3F)C5CC5

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 371.41 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Gu JW, Fang W, Chin NX, Neu HC. In vitro activity of CP-74,667. A new fluoroquinolone compared with other quinolones. Diagn Microbiol Infect Dis. 1992 Sep-Oct;15(7):613-20. PubMed PMID: 1330421.

2: Jones RN, Erwin ME. In vitro activity of CP-74667 compared with four other fluoroquinolones. Diagn Microbiol Infect Dis. 1992 Aug;15(6):531-6. PubMed PMID: 1330419.

3: Girard D, Gootz TD, McGuirk PR. Pharmacokinetic studies of CP-74,667, a new quinolone, in laboratory animals. Antimicrob Agents Chemother. 1992 Aug;36(8):1671-6. PubMed PMID: 1329625; PubMed Central PMCID: PMC192028.