WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 319906
Description: Faxeladol, also known as GCR9905, GRT-TA300, GRTA0009906, EM-906 and GRTA9906, is an opioid analgesic agent. Faxeladol is related to tramadol and ciramadol, and was developed shortly after tramadol in the late 1970s. Similarly to tramadol, it was believed faxeladol would have analgesic, as well as antidepressant effects, due to its action on serotonin and norepinephrine reuptake. In various studies in the 1970s alongside tramadol, faxeladol was seen to be slightly more potent than tramadol, but with a higher rate of sudden seizures than tramadol, which is known to cause seizures without warning in some users.
MedKoo Cat#: 319906
Chemical Formula: C15H23NO
Exact Mass: 233.178
Molecular Weight: 233.355
Elemental Analysis: C, 77.21; H, 9.94; N, 6.00; O, 6.86
Synonym: GCR9905; GCR 9905; GCR-9905; EM-906; EM 906; EM906; GRT-TA300; GRTA9906; GRTA-9906; GRTA 9906; GRTA0009906; GRTA-0009906;GRTA 0009906;Faxeladol
IUPAC/Chemical Name: 3-((1R,2R)-2-((dimethylamino)methyl)cyclohexyl)phenol
InChi Key: JIRYWFYYBBRJAN-ZFWWWQNUSA-N
InChi Code: InChI=1S/C15H23NO/c1-16(2)11-13-6-3-4-9-15(13)12-7-5-8-14(17)10-12/h5,7-8,10,13,15,17H,3-4,6,9,11H2,1-2H3/t13-,15-/m0/s1
SMILES Code: OC1=CC=CC([C@H]2[C@H](CN(C)C)CCCC2)=C1
1: Sindrup SH, Konder R, Lehmann R, Meier T, Winkel M, Ashworth J, Baron R, Jensen TS. Randomized controlled trial of the combined monoaminergic and opioid investigational compound GRT9906 in painful polyneuropathy. Eur J Pain. 2012 Jul;16(6):849-59. doi: 10.1002/j.1532-2149.2011.00069.x. PubMed PMID: 22337471.