Faxeladol

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 319906

CAS#: 433265-65-7

Description: Faxeladol, also known as GCR9905, GRT-TA300, GRTA0009906, EM-906 and GRTA9906, is an opioid analgesic agent. Faxeladol is related to tramadol and ciramadol, and was developed shortly after tramadol in the late 1970s. Similarly to tramadol, it was believed faxeladol would have analgesic, as well as antidepressant effects, due to its action on serotonin and norepinephrine reuptake. In various studies in the 1970s alongside tramadol, faxeladol was seen to be slightly more potent than tramadol, but with a higher rate of sudden seizures than tramadol, which is known to cause seizures without warning in some users.


Price and Availability

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Faxeladol is not in stock, but may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 319906
Name: Faxeladol
CAS#: 433265-65-7
Chemical Formula: C15H23NO
Exact Mass: 233.178
Molecular Weight: 233.355
Elemental Analysis: C, 77.21; H, 9.94; N, 6.00; O, 6.86


Synonym: GCR9905; GCR 9905; GCR-9905; EM-906; EM 906; EM906; GRT-TA300; GRTA9906; GRTA-9906; GRTA 9906; GRTA0009906; GRTA-0009906;GRTA 0009906;Faxeladol

IUPAC/Chemical Name: 3-((1R,2R)-2-((dimethylamino)methyl)cyclohexyl)phenol

InChi Key: JIRYWFYYBBRJAN-ZFWWWQNUSA-N

InChi Code: InChI=1S/C15H23NO/c1-16(2)11-13-6-3-4-9-15(13)12-7-5-8-14(17)10-12/h5,7-8,10,13,15,17H,3-4,6,9,11H2,1-2H3/t13-,15-/m0/s1

SMILES Code: OC1=CC=CC([C@H]2[C@H](CN(C)C)CCCC2)=C1


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO, not in water

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

1: Sindrup SH, Konder R, Lehmann R, Meier T, Winkel M, Ashworth J, Baron R, Jensen TS. Randomized controlled trial of the combined monoaminergic and opioid investigational compound GRT9906 in painful polyneuropathy. Eur J Pain. 2012 Jul;16(6):849-59. doi: 10.1002/j.1532-2149.2011.00069.x. PubMed PMID: 22337471.