NOTA-cyclic RGDyK

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MedKoo CAT#: 125673


Description: NOTA-cyclic RGDyK is a ligand to bind 68Ga for molecular imaging of αvβ3 integrin overexpressing tumor.

Chemical Structure

NOTA-cyclic RGDyK

Theoretical Analysis

MedKoo Cat#: 125673
Name: NOTA-cyclic RGDyK
Chemical Formula: C39H60N12O13
Exact Mass: 904.44
Molecular Weight: 904.980
Elemental Analysis: C, 51.76; H, 6.68; N, 18.57; O, 22.98

Price and Availability

Size Price Availability Quantity
10mg USD 1250 2 Weeks
50mg USD 2050 2 Weeks
100mg USD 3850 2 Weeks
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Synonym: NOTA-cyclic RGDyK; NOTA cyclic RGDyK; NOTA cyclic-RGDyK

IUPAC/Chemical Name: 2,2'-(7-(2-((4-(11-(carboxymethyl)-5-(3-guanidinopropyl)-14-(4-hydroxybenzyl)-3,6,9,12,15-pentaoxo-1,4,7,10,13-pentaazacyclopentadecan-2-yl)butyl)amino)-2-oxoethyl)-1,4,7-triazonane-1,4-diyl)diacetic acid


InChi Code: InChI=1S/C39H60N12O13/c40-39(41)43-11-3-5-26-35(61)44-20-30(53)45-29(19-32(55)56)38(64)48-28(18-24-6-8-25(52)9-7-24)37(63)47-27(36(62)46-26)4-1-2-10-42-31(54)21-49-12-14-50(22-33(57)58)16-17-51(15-13-49)23-34(59)60/h6-9,26-29,52H,1-5,10-23H2,(H,42,54)(H,44,61)(H,45,53)(H,46,62)(H,47,63)(H,48,64)(H,55,56)(H,57,58)(H,59,60)(H4,40,41,43)


Appearance: To be determined

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 904.98 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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Kim JH, Kim YH, Kim YJ, Yang BY, Jeong JM, Youn H, Lee DS, Lee JS. Quantitative positron emission tomography imaging of angiogenesis in rats with forelimb ischemia using (68)Ga-NOTA-c(RGDyK). Angiogenesis. 2013 Oct;16(4):837-46. doi: 10.1007/s10456-013-9359-4. Epub 2013 Jul 16. PMID: 23857293.