S-Tenatoprazole sodium

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 125393

CAS#: 705968-89-4

Description: S-TENATOPRAZOLE SODIUM: A PROMISING NEW PROTON PUMP INHIBITOR WITH A SAFE GENERAL PHARMACOLOGICAL PROFILE.

Chemical Structure

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S-Tenatoprazole sodium
CAS# 705968-89-4
Instruction

Theoretical Analysis

MedKoo Cat#: 125393
Name: S-Tenatoprazole sodium
CAS#: 705968-89-4
Chemical Formula: C16H17N4NaO3S
Exact Mass: 368.09
Molecular Weight: 368.390
Elemental Analysis: C, 52.17; H, 4.65; N, 15.21; Na, 6.24; O, 13.03; S, 8.70

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: S-Tenatoprazole-Na; S-Tenatoprazole sodium; Sodium S-tenatoprazole; (-)-Tenatoprazole sodium salt; A6Y903H52E

IUPAC/Chemical Name: sodium 5-methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)imidazo[4,5-b]pyridin-1-ide

InChi Key: FEOTUYWTBYAGEV-JIDHJSLPSA-N

InChi Code: InChI=1S/C16H17N4O3S.Na/c1-9-7-17-12(10(2)14(9)23-4)8-24(21)16-18-11-5-6-13(22-3)19-15(11)20-16;/h5-7H,8H2,1-4H3;/q-1;+1/t24-;/m0./s1

SMILES Code: [Na+].COC1=CC=C2[N-]C(=NC2=N1)[S@@+]([O-])CC3=NC=C(C)C(OC)=C3C

Appearance: To be determined

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 368.39 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Hunt RH, Armstrong D, Yaghoobi M, James C. The pharmacodynamics and
pharmacokinetics of S-tenatoprazole-Na 30 mg, 60 mg and 90 mg vs. esomeprazole
40 mg in healthy male subjects. Aliment Pharmacol Ther. 2010 Mar;31(6):648-57.
doi: 10.1111/j.1365-2036.2009.04219.x. Epub 2009 Dec 15. PMID: 20015104.

2: Tomillero A, Moral MA. Gateways to clinical trials. Methods Find Exp Clin
Pharmacol. 2008 Oct;30(8):643-72. PMID: 19088949.

3: Shin JM, Homerin M, Domagala F, Ficheux H, Sachs G. Characterization of the
inhibitory activity of tenatoprazole on the gastric H+,K+ -ATPase in vitro and
in vivo. Biochem Pharmacol. 2006 Mar 14;71(6):837-49. doi:
10.1016/j.bcp.2005.11.030. Epub 2006 Jan 10. PMID: 16405921.