WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 556213

CAS#: 2490311-14-1

Description: CUN11141, also known as BRD4 Inhibitor-20, is a potent orally active bromodomain protein 4 (BRD4) inhibitor. It can be used for the research of kinds of cancer, such as colon cancer. This compound was first reported in European Journal of Medicinal Chemistry (2020), 208, 112780. This product has no formal name at the moment. For the convenience of communication, a temporal code name was therefore proposed according to MedKoo Chemical Nomenclature (see web page:

Chemical Structure

CAS# 2490311-14-1

Theoretical Analysis

MedKoo Cat#: 556213
Name: CUN11141
CAS#: 2490311-14-1
Chemical Formula: C18H18N2O4S
Exact Mass: 358.10
Molecular Weight: 358.412
Elemental Analysis: C, 60.32; H, 5.06; N, 7.82; O, 17.86; S, 8.95

Price and Availability

Size Price Availability Quantity
100mg USD 1650 2 Weeks
1g USD 4650 2 Weeks
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Synonym: BRD4 Inhibitor-20 ; CUN11141; CUN-11141; CUN 11141;

IUPAC/Chemical Name: Benzenesulfonamide, N-[2,3-dihydro-3-(1-methylethylidene)-2-oxo-1H-indol-5-yl]-2-methoxy-


InChi Code: InChI=1S/C18H18N2O4S/c1-11(2)17-13-10-12(8-9-14(13)19-18(17)21)20-25(22,23)16-7-5-4-6-15(16)24-3/h4-10,20H,1-3H3,(H,19,21)

SMILES Code: O=S(C1=CC=CC=C1OC)(NC2=CC3=C(NC(/C3=C(C)/C)=O)C=C2)=O

Appearance: To be determined

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 358.41 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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Xu Y, Zhang XJ, Li WB, Wang XR, Wang S, Qiao XP, Chen SW. Design, synthesis and biological evaluation of indole-2-one derivatives as potent BRD4 inhibitors. Eur J Med Chem. 2020 Dec 15;208:112780. doi: 10.1016/j.ejmech.2020.112780. Epub 2020 Aug 30. PMID: 32883643.