2'-Deoxyuridine 5'-monophosphate disodium salt
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MedKoo CAT#: 122557

CAS#: 42155-08-8

Description: 2'-Deoxyuridine 5'-monophosphate disodium salt is a nucleoside analog that inhibits the synthesis of DNA and RNA by inhibiting the enzyme thymidylate synthase, which prevents the formation of dTMP from deoxyuridine 5'-triphosphate.

Chemical Structure

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2'-Deoxyuridine 5'-monophosphate disodium salt
CAS# 42155-08-8
Instruction

Theoretical Analysis

MedKoo Cat#: 122557
Name: 2'-Deoxyuridine 5'-monophosphate disodium salt
CAS#: 42155-08-8
Chemical Formula: C9H11N2Na2O8P
Exact Mass: 352.00
Molecular Weight: 352.150
Elemental Analysis: C, 30.70; H, 3.15; N, 7.96; Na, 13.06; O, 36.35; P, 8.80

Price and Availability

Size Price Availability Quantity
250mg USD 350 2 Weeks
500mg USD 650 2 Weeks
1g USD 950 2 Weeks
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Synonym: Disodium 2'-deoxyuridylate; 2'-Deoxyuridine 5'-monophosphate disodium salt; 5'-Uridylic acid, 2'-deoxy-, disodium salt; 6AG9V4748N

IUPAC/Chemical Name: sodium ((2R,3S,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl)methyl phosphate

InChi Key: FXVXMLXAXVVONE-CDNBRZBRSA-L

InChi Code: InChI=1S/C9H13N2O8P.2Na/c12-5-3-8(11-2-1-7(13)10-9(11)14)19-6(5)4-18-20(15,16)17;;/h1-2,5-6,8,12H,3-4H2,(H,10,13,14)(H2,15,16,17);;/q;2*+1/p-2/t5-,6+,8+;;/m0../s1

SMILES Code: O[C@@H](C[C@H](N1C(NC(C=C1)=O)=O)O2)[C@H]2COP([O-])([O-])=O.[Na+].[Na+]

Appearance: To be determined

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 352.15 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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Funk RS, van Haandel L, Becker ML, Leeder JS. Low-dose methotrexate results in the selective accumulation of aminoimidazole carboxamide ribotide in an erythroblastoid cell line. J Pharmacol Exp Ther. 2013 Oct;347(1):154-63. doi: 10.1124/jpet.113.206672. Epub 2013 Jul 25. PMID: 23887097; PMCID: PMC3781408.