2'-Deoxyuridine
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MedKoo CAT#: 122499

CAS#: 951-78-0

Description: 2'-Deoxyuridine has been shown to inhibit the enzymatic activity of enzymes responsible for synthesizing uridine and thymidylate, leading to neuronal death.

Chemical Structure

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2'-Deoxyuridine
CAS# 951-78-0
Instruction

Theoretical Analysis

MedKoo Cat#: 122499
Name: 2'-Deoxyuridine
CAS#: 951-78-0
Chemical Formula: C9H12N2O5
Exact Mass: 228.07
Molecular Weight: 228.200
Elemental Analysis: C, 47.37; H, 5.30; N, 12.28; O, 35.05

Price and Availability

Size Price Availability Quantity
25g USD 350 2 Weeks
50g USD 650 2 Weeks
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Synonym: 2'-DEOXYURIDINE; 951-78-0; deoxyuridine; Uracil deoxyriboside; Uridine, 2'-deoxy-

IUPAC/Chemical Name: 1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione

InChi Key: MXHRCPNRJAMMIM-SHYZEUOFSA-N

InChi Code: InChI=1S/C9H12N2O5/c12-4-6-5(13)3-8(16-6)11-2-1-7(14)10-9(11)15/h1-2,5-6,8,12-13H,3-4H2,(H,10,14,15)/t5-,6+,8+/m0/s1

SMILES Code: OC[C@@H]1[C@H](C[C@H](N2C(NC(C=C2)=O)=O)O1)O

Appearance: To be determined

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 228.20 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Chenna A, Iden CR. Characterization of 2'-deoxycytidine and 2'-deoxyuridine
adducts formed in reactions with acrolein and 2-bromoacrolein. Chem Res Toxicol.
1993 May-Jun;6(3):261-8. doi: 10.1021/tx00033a003. PMID: 8318647.

2: Michalska L, Wawrzyniak D, Szymańska-Michalak A, Barciszewski J, Boryski J,
Baraniak D. Synthesis and biological assay of new 2'-deoxyuridine dimers
containing a 1,2,3-triazole linker. Part I. Nucleosides Nucleotides Nucleic
Acids. 2019;38(3):218-235. doi: 10.1080/15257770.2018.1514122. Epub 2018 Dec 27.
PMID: 30588866.

3: Mori S, Morihiro K, Obika S. C5-azobenzene-substituted 2'-deoxyuridine-
containing oligodeoxynucleotides for photo-switching hybridization. Molecules.
2014 Apr 22;19(4):5109-18. doi: 10.3390/molecules19045109. PMID: 24759071;
PMCID: PMC6271114.