BP Lipid 143
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MedKoo CAT#: 122291

CAS#: N/A

Description: BP Lipid 143 is an ionizable amino lipid with propanolamine head which can efficiently encapsulate mRNA. Ester linkages are incorporated, at C7 adn C6 position relative to amine, in the structure to increase tissue clearance of the lipid in the liver. The primary ester has a 7-carbons lipid tail. The lipid can be used for mRNA-based therapies which depends on the availability of a safe and efficient delivery vehicle.

Chemical Structure

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BP Lipid 143
CAS# N/A
Instruction

Theoretical Analysis

MedKoo Cat#: 122291
Name: BP Lipid 143
CAS#: N/A
Chemical Formula: C40H79NO5
Exact Mass: 653.60
Molecular Weight: 654.070
Elemental Analysis: C, 73.45; H, 12.17; N, 2.14; O, 12.23

Price and Availability

Size Price Availability Quantity
50mg USD 800 2 Weeks
100mg USD 1300 2 Weeks
250mg USD 2150 2 Weeks
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Synonym: BP Lipid 143; BP-26400; CS-0435708; Heptyl 7-((6-(heptadecan-9-yloxy)-6-oxohexyl)(3-hydroxypropyl)amino)heptanoate

IUPAC/Chemical Name: heptyl 7-((6-(heptadecan-9-yloxy)-6-oxohexyl)(3-hydroxypropyl)amino)heptanoate

InChi Key: LPTJFFFRDQIERN-UHFFFAOYSA-N

InChi Code: InChI=1S/C40H79NO5/c1-4-7-10-13-15-21-29-38(30-22-16-14-11-8-5-2)46-40(44)32-24-20-26-34-41(35-28-36-42)33-25-18-17-23-31-39(43)45-37-27-19-12-9-6-3/h38,42H,4-37H2,1-3H3

SMILES Code: OCCCN(CCCCCC(OC(CCCCCCCC)CCCCCCCC)=O)CCCCCCC(OCCCCCCC)=O

Appearance: To be determined

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 654.07 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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