GL67
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 122233

CAS#: N/A

Description: GL67 is a cationic lipid composed of cholesterol coupled to spermine. GL67 may be used to mediate gene transfer into mammalian cells. This lipid was a critical component for successfully completed clinical studies in the delivery of pDNA via inhalation.

Chemical Structure

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GL67
CAS# N/A
Instruction

Theoretical Analysis

MedKoo Cat#: 122233
Name: GL67
CAS#: N/A
Chemical Formula: C38H70N4O2
Exact Mass: 614.55
Molecular Weight: 615.000
Elemental Analysis: C, 74.21; H, 11.47; N, 9.11; O, 5.20

Price and Availability

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5mg USD 550 2 Weeks
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Synonym: LF47XVU5BD; N4-Spermine cholesterol carbamate

IUPAC/Chemical Name: (3S,10R,13R,17R)-10,13-dimethyl-17-((R)-6-methylheptan-2-yl)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl (3-aminopropyl)(4-((3-aminopropyl)amino)butyl)carbamate

InChi Key: KBBLYWGVXTZWCU-FWAFJIPTSA-N

InChi Code: InChI=1S/C38H70N4O2/c1-28(2)11-8-12-29(3)33-15-16-34-32-14-13-30-27-31(17-19-37(30,4)35(32)18-20-38(33,34)5)44-36(43)42(26-10-22-40)25-7-6-23-41-24-9-21-39/h13,28-29,31-35,41H,6-12,14-27,39-40H2,1-5H3/t29-,31+,32?,33-,34?,35?,37+,38-/m1/s1

SMILES Code: NCCCNCCCCN(CCCN)C(O[C@@H]1CC2=CCC(C(CC[C@@H]3[C@H](C)CCCC(C)C)[C@]3(C)CC4)C4[C@@]2(C)CC1)=O

Appearance: To be determined

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 615.00 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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