S07-2010

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 121025

CAS#: 1223194-71-5

Description: S07-2010 is an AKR1C3 inhibitor. S07-2010 may serve as promising therapeutic adjuvants toward new therapeutics for countering drug resistance.


Chemical Structure

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S07-2010
CAS# 1223194-71-5

Theoretical Analysis

MedKoo Cat#: 121025
Name: S07-2010
CAS#: 1223194-71-5
Chemical Formula: C19H21N3O3S
Exact Mass: 371.1304
Molecular Weight: 371.455
Elemental Analysis: C, 61.44; H, 5.70; N, 11.31; O, 12.92; S, 8.63

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: S-07-2010; S07-2010; S 07-2010

IUPAC/Chemical Name: 7-(2-((6-oxo-4-propyl-1,6-dihydropyrimidin-2-yl)thio)acetyl)-1,3,4,5-tetrahydro-2H-benzo[b]azepin-2-one

InChi Key: WVRKQDZPZOUPNW-UHFFFAOYSA-N

InChi Code: InChI=1S/C19H21N3O3S/c1-2-4-14-10-18(25)22-19(20-14)26-11-16(23)13-7-8-15-12(9-13)5-3-6-17(24)21-15/h7-10H,2-6,11H2,1H3,(H,21,24)(H,20,22,25)

SMILES Code: CCCC1=CC(NC(SCC(C2=CC3=C(NC(CCC3)=O)C=C2)=O)=N1)=O

Appearance: To be determined

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 371.455 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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He S, Liu Y, Chu X, Li Q, Lyu W, Liu Y, Xing S, Feng F, Liu W, Guo Q, Zhao L, Sun H. Discovery of Novel Aldo-Keto Reductase 1C3 Inhibitors as Chemotherapeutic Potentiators for Cancer Drug Resistance. ACS Med Chem Lett. 2022 Jul 8;13(8):1286-1294. doi: 10.1021/acsmedchemlett.2c00175. PMID: 35978698; PMCID: PMC9377021.