DS-3801b di-L-tartrate

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 208285

CAS#: 1369412-66-7

Description: DS-3801b di-L-tartrate is a gastrointestinal (GI) hormone and is involved in the regulation of GI motility through binding to GPR38, the motilin receptor which is expressed on smooth muscle cells in the GI tract

Chemical Structure

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DS-3801b di-L-tartrate
CAS# 1369412-66-7
Instruction

Theoretical Analysis

MedKoo Cat#: 208285
Name: DS-3801b di-L-tartrate
CAS#: 1369412-66-7
Chemical Formula: C36H51N3O15
Exact Mass: 765.33
Molecular Weight: 765.810
Elemental Analysis: C, 56.46; H, 6.71; N, 5.49; O, 31.34

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: DS3801b di-L-tartrate, DS3801b diL-tartrate, DS3801b diLtartrate

IUPAC/Chemical Name: (S)-4-(3-(Hydroxymethyl)phenoxy)-N-methyl-N-(3-methyl-4-((3-methylpiperazin-1-yl)methyl)phenyl)cyclohexane-1-carboxamide di-L(+)-tartrate

InChi Key: NXWFUWCIIBJRMJ-AZNJGZCLSA-N

InChi Code: InChI=1S/C28H39N3O3.2C4H6O6/c1-20-15-25(10-7-24(20)18-31-14-13-29-21(2)17-31)30(3)28(33)23-8-11-26(12-9-23)34-27-6-4-5-22(16-27)19-32;2*5-1(3(7)8)2(6)4(9)10/h4-7,10,15-16,21,23,26,29,32H,8-9,11-14,17-19H2,1-3H3;2*1-2,5-6H,(H,7,8)(H,9,10)/t21-,23?,26?;2*1-,2-/m011/s1

SMILES Code: CN(C(C1CCC(OC2=CC=CC(CO)=C2)CC1)=O)C3=CC(C)=C(CN4C[C@H](C)NCC4)C=C3.OC([C@H](O)[C@@H](O)C(O)=O)=O.OC([C@H](O)[C@@H](O)C(O)=O)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 765.81 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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Toda N, Shida T, Takano R, Katagiri T, Hirouchi M, Abe M, Soma K, Nakagami Y, Yamazaki M. Discovery of DS-3801b, a non-macrolide GPR38 agonist with N-methylanilide structure. Bioorg Med Chem Lett. 2022 Mar 1;59:128554. doi: 10.1016/j.bmcl.2022.128554. Epub 2022 Jan 18. PMID: 35051575.