Buphedrone

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 576904

CAS#: 408332-79-6

Description: Buphedrone is a stimulant of the phenethylamine and cathinone chemical classes. Buphedrone as a free base is very unstable; the ketone is readily reduced to a hydroxyl group, thus forming the corresponding alcohol. Structurally, this occurs when the C=O bond at the Rβ-position is converted into a C-OH bond. Because of this, it is sold as various salts, with a hydrochloride being most common. This product is for RESEARCH USE ONLY and will only be shipped to research universities or institutions.

Chemical Structure

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Buphedrone
CAS# 408332-79-6
Instruction

Theoretical Analysis

MedKoo Cat#: 576904
Name: Buphedrone
CAS#: 408332-79-6
Chemical Formula: C11H15NO
Exact Mass: 177.12
Molecular Weight: 177.250
Elemental Analysis: C, 74.54; H, 8.53; N, 7.90; O, 9.03

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: Buphedrone; MABP

IUPAC/Chemical Name: alpha-Methylamino-butyrophenone

InChi Key: DDPMGIMJSRUULN-UHFFFAOYSA-N

InChi Code: InChI=1S/C11H15NO/c1-3-10(12-2)11(13)9-7-5-4-6-8-9/h4-8,10,12H,3H2,1-2H3

SMILES Code: CCC(NC)C(=O)c1ccccc1

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 177.25 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1. Carrola J, Duarte N, Florindo P, Henriques S, da Silva G, Bijlsma L, Moreira R, Correia C, Perry MJ, Lopes Á, de Mello-Sampayo C, Bronze MDR. Metabolism of N-ethylhexedrone and buphedrone: An in vivo study in mice using HPLC-MS/MS. J Chromatogr B Analyt Technol Biomed Life Sci. 2020 Nov 30;1159:122340. doi: 10.1016/j.jchromb.2020.122340. Epub 2020 Aug 25. PMID: 32905991.

2. Oh JH, Hwang JY, Hong SI, Ma SX, Seo JY, Lee SY, Kim HC, Jang CG. The new designer drug buphedrone produces rewarding properties via dopamine D1 receptor activation. Addict Biol. 2018 Jan;23(1):69-79. doi: 10.1111/adb.12472. Epub 2016 Oct 27. PMID: 27790823.