Pimetine hydrochloride

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 576645

CAS#: 4991-68-8 (HCl)

Description: Pimetine hydrochloride is an antihyperlipoproteinemic.

Chemical Structure

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Pimetine hydrochloride
CAS# 4991-68-8 (HCl)
Instruction

Theoretical Analysis

MedKoo Cat#: 576645
Name: Pimetine hydrochloride
CAS#: 4991-68-8 (HCl)
Chemical Formula: C16H28Cl2N2
Exact Mass: 318.16
Molecular Weight: 319.310
Elemental Analysis: C, 60.18; H, 8.84; Cl, 22.20; N, 8.77

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Related CAS #: 3565-03-5 (free base); 4991-68-8 (HCl)  

Synonym: Pimetine hydrochloride; Pimetine HCl; IN 379; IN379; IN-379

IUPAC/Chemical Name: 4-Benzyl-1-(2-(dimethylamino)ethyl)piperidine dihydrochloride

InChi Key: XZRWNULNYWMWBM-UHFFFAOYSA-N

InChi Code: InChI=1S/C16H26N2.2ClH/c1-17(2)12-13-18-10-8-16(9-11-18)14-15-6-4-3-5-7-15;;/h3-7,16H,8-14H2,1-2H3;2*1H

SMILES Code: Cl.Cl.CN(C)CCN1CCC(Cc2ccccc2)CC1

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 319.31 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1. Hollister LE. A comparison of pimetine with amphetamine and of tybamate with meprobamate. J New Drugs. 1966 Nov-Dec;6(6):339-44. doi: 10.1177/009127006600600604. PMID: 5976158.

2. Karol B, Brown ML, Sletten IW. Behavioral and arterial pressure effects of pimetine in conscious dogs. Eur J Pharmacol. 1967 Jul;1(4):342-6. doi: 10.1016/0014-2999(67)90077-5. PMID: 6082309.

3. Cohen BM. A progress note on pimetine hydrochloride in obstructive ventilatory disease. Med Thorac. 1967;24(5):306-17. doi: 10.1159/000192535. PMID: 6062494.