Cuprimyxin

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 413380

CAS#: 28069-65-0

Description: Cuprimyxin is a topical antibiotic with considerable antibacterial, anti-yeast, and antifungal activity in veterinary applications without the irritation side effects.

Chemical Structure

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Cuprimyxin
CAS# 28069-65-0
Instruction

Theoretical Analysis

MedKoo Cat#: 413380
Name: Cuprimyxin
CAS#: 28069-65-0
Chemical Formula: C26H18CuN4O8
Exact Mass: 577.04
Molecular Weight: 577.990
Elemental Analysis: C, 54.03; H, 3.14; Cu, 10.99; N, 9.69; O, 22.14

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: Cuprimyxin; NSC136768; NSC-136768; NSC 136768

IUPAC/Chemical Name: copper(II) 1-methoxy-6-oxidophenazine 5,10-dioxide

InChi Key: WMZHLGPNUXTHSP-UHFFFAOYSA-L

InChi Code: InChI=1S/2C13H10N2O4.Cu/c2*1-19-11-7-3-5-9-13(11)15(18)8-4-2-6-10(16)12(8)14(9)17;/h2*2-7,16H,1H3;/q;;+2/p-2

SMILES Code: COc(cccc12)c1n(=O)c(cccc3[O-])c3n2=O.COc(cccc45)c4n(=O)c(cccc6[O-])c6n5=O.[Cu+2]

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
Soluble in DMSO 0.0 100.00

Preparing Stock Solutions

The following data is based on the product molecular weight 577.99 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Snyder WE, Imhoff RK. Cuprimyxin a new topical antibiotic. Vet Med Small Anim Clin. 1975 Dec;70(12):1421-3. PMID: 1043546.

2: Maestrone G, Brandt W. Evaluation of a cuprimyxin-hydrocortisone acetate suspension in the treatment of otitis externa in dogs and cats. Am J Vet Res. 1979 Feb;40(2):285-7. PMID: 464367.

3: Manius G, Tscherne R, Venteicher R, Secker A. High-performance liquid chromatographic determination of free myxin and its reduction product as impurities in cuprimyxin-containing creams. J Pharm Sci. 1981 Sep;70(9):1024-6. doi: 10.1002/jps.2600700914. PMID: 6101146.

4: Maestrone G, Brandt W. Evaluation of two cuprimyxin formulations in the treatment of cutaneous and ophthalmic infections in horses and cattle. Vet Med Small Anim Clin. 1980 Aug;75(8):1307-11. PMID: 6903045.