GP-531 tartrate

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 575950

CAS#: 911205-04-4

Description: GP-531 tartrate is an adenosine-regulating agent with cardioprotective effects.

Chemical Structure

img
GP-531 tartrate
CAS# 911205-04-4
Instruction

Theoretical Analysis

MedKoo Cat#: 575950
Name: GP-531 tartrate
CAS#: 911205-04-4
Chemical Formula: C20H27N5O10
Exact Mass: 497.18
Molecular Weight: 497.460
Elemental Analysis: C, 48.29; H, 5.47; N, 14.08; O, 32.16

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: GP-531 tartrate; GP 531 tartrate; GP531 tartrate

IUPAC/Chemical Name: 1H-Imidazole-4-carboxamide, 5-amino-1-(5-deoxy-5-((phenylmethyl)amino)-beta-D-ribofuranosyl)-, (2R,3R)-2,3-dihydroxybutanedioate (1:1)

InChi Key: VKQWMBKJUARLCQ-REMRMEERSA-N

InChi Code: InChI=1S/C16H21N5O4.C4H6O6/c17-14-11(15(18)24)20-8-21(14)16-13(23)12(22)10(25-16)7-19-6-9-4-2-1-3-5-9;5-1(3(7)8)2(6)4(9)10/h1-5,8,10,12-13,16,19,22-23H,6-7,17H2,(H2,18,24);1-2,5-6H,(H,7,8)(H,9,10)/t10-,12-,13-,16-;1-,2-/m11/s1

SMILES Code: NC(=O)c1ncn([C@@H]2O[C@H](CNCc3ccccc3)[C@@H](O)[C@H]2O)c1N.O[C@H]([C@@H](O)C(=O)O)C(=O)O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 497.46 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

1. Hale SL, Kloner RA. Cardioprotection with adenosine-regulating agent, GP531: effects on no-reflow, infarct size, and blood flow following ischemia/ reperfusion in the rabbit. J Cardiovasc Pharmacol Ther. 2010 Mar;15(1):60-7. doi: 10.1177/1074248409357742. PMID: 20133497.

2. Kurz MA, Bullough DA, Buggé CJ, Mullane KM, Young MA. Cardioprotection with a novel adenosine regulating agent mediated by intravascular adenosine. Eur J Pharmacol. 1997 Mar 19;322(2-3):211-20. doi: 10.1016/s0014-2999(97)00011-3. PMID: 9098689.

3. Chen LS, Fujitaki JM, Dixon R. A sensitive assay for the aminoimidazole-containing drug GP531 in plasma using liquid chromatography with amperometric electrochemical detection: a new class of electroactive compounds. J Pharm Biomed Anal. 1996 Aug;14(11):1535-8. doi: 10.1016/0731-7085(95)01719-4. PMID: 8877860.