GK-101E

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 575877

CAS#: 77416-67-2

Description: GK-101E is a biochemical that may be useful in removing carious material from tooth or bone.

Chemical Structure

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GK-101E
CAS# 77416-67-2
Instruction

Theoretical Analysis

MedKoo Cat#: 575877
Name: GK-101E
CAS#: 77416-67-2
Chemical Formula: C4H8ClNO2
Exact Mass: 137.02
Molecular Weight: 137.560
Elemental Analysis: C, 34.93; H, 5.86; Cl, 25.77; N, 10.18; O, 23.26

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: Caridex; GK-101E; GK 101E; GK101E

IUPAC/Chemical Name: Butanoic acid, 2-(chloroamino)-, (+-)-

InChi Key: AZWATAMGZFKYHZ-UHFFFAOYSA-N

InChi Code: InChI=1S/C4H8ClNO2/c1-2-3(6-5)4(7)8/h3,6H,2H2,1H3,(H,7,8)

SMILES Code: CCC(NCl)C(=O)O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 137.56 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1. Schutzbank SG, Galaini J, Kronman JH, Goldman M, Clark RE. A comparative in vitro study of GK-101 and GK-101E in caries removal. J Dent Res. 1978 Sep-Oct;57(9-10):861-4. doi: 10.1177/00220345780570090201. PMID: 281357.

2. Hamama H, Yiu C, Burrow M. Current update of chemomechanical caries removal methods. Aust Dent J. 2014 Dec;59(4):446-56; quiz 525. doi: 10.1111/adj.12214. Epub 2014 Sep 26. PMID: 25131424.

3. Maragakis GM, Hahn P, Hellwig E. Chemomechanical caries removal: a comprehensive review of the literature. Int Dent J. 2001 Aug;51(4):291-9. doi: 10.1002/j.1875-595x.2001.tb00841.x. PMID: 11570545.