Cl 13850

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 412994

CAS#: 13018-60-5

Description: Cl 13850 is a biochemical with carbonic anhydrase activity

Chemical Structure

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Cl 13850
CAS# 13018-60-5
Instruction

Theoretical Analysis

MedKoo Cat#: 412994
Name: Cl 13850
CAS#: 13018-60-5
Chemical Formula: C8H14N4O3S2
Exact Mass: 278.05
Molecular Weight: 278.350
Elemental Analysis: C, 34.52; H, 5.07; N, 20.13; O, 17.24; S, 23.04

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: Cl 13850; Cl13850; Cl-13850

IUPAC/Chemical Name: Acetamide, N-(5-(((1,1-dimethylethyl)amino)sulfonyl)-1,3,4-thiadiazol-2-yl)-

InChi Key: XQSQJQIWDZTQCE-UHFFFAOYSA-N

InChi Code: InChI=1S/C8H14N4O3S2/c1-5(13)9-6-10-11-7(16-6)17(14,15)12-8(2,3)4/h12H,1-4H3,(H,9,10,13)

SMILES Code: CC(NC1=NN=C(S(=O)(NC(C)(C)C)=O)S1)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 278.35 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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6: Hall GE, Kenny AD. Bone resorption induced by parathyroid hormone and dibutyryl cyclic AMP: role of carbonic anhydrase. J Pharmacol Exp Ther. 1986 Sep;238(3):778-82. PMID: 3018220.

7: Nichols FC, Neuman WF. Lactic acid production in mouse calvaria in vitro with and without parathyroid hormone stimulation: lack of acetazolamide effects. Bone. 1987;8(2):105-9. doi: 10.1016/8756-3282(87)90078-0. PMID: 3593606.

8: Hall GE, Kenny AD. Role of carbonic anhydrase in bone resorption induced by 1,25 dihydroxyvitamin D3 in vitro. Calcif Tissue Int. 1985 Mar;37(2):134-42. doi: 10.1007/BF02554832. PMID: 3924369.

9: Coates EL, Li AH, Nattie EE. Acetazolamide on the ventral medulla of the cat increases phrenic output and delays the ventilatory response to CO2. J Physiol. 1991 Sep;441:433-51. doi: 10.1113/jphysiol.1991.sp018760. PMID: 1816381; PMCID: PMC1180207.