Auriclosene monosodium

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 575115

CAS#: 1073913-47-9

Description: Auriclosene monosodium is a potent broad spectrum antimicrobial agent.

Chemical Structure

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Auriclosene monosodium
CAS# 1073913-47-9
Instruction

Theoretical Analysis

MedKoo Cat#: 575115
Name: Auriclosene monosodium
CAS#: 1073913-47-9
Chemical Formula: C4H8Cl2NNaO3S
Exact Mass: 242.95
Molecular Weight: 244.060
Elemental Analysis: C, 19.69; H, 3.30; Cl, 29.05; N, 5.74; Na, 9.42; O, 19.67; S, 13.14

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: Auriclosene monosodium; Auriclosene monosodium anhydrous

IUPAC/Chemical Name: 1-Propanesulfonic acid, 2-(dichloroamino)-2-methyl-, sodium salt (1:1)

InChi Key: NMHCZZRJHKDTBE-UHFFFAOYSA-M

InChi Code: InChI=1S/C4H9Cl2NO3S.Na/c1-4(2,7(5)6)3-11(8,9)10;/h3H2,1-2H3,(H,8,9,10);/q;+1/p-1

SMILES Code: [Na+].CC(C)(CS(=O)(=O)[O-])N(Cl)Cl

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 244.06 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Rani SA, Celeri C, Najafi R, Bley K, Debabov D. Irrigation with N,N-dichloro-2,2-dimethyltaurine (NVC-422) in a citrate buffer maintains urinary catheter patency in vitro and prevents encrustation by Proteus mirabilis. Urolithiasis. 2015 Aug 18. [Epub ahead of print] PubMed PMID: 26282899.

2: Gupta AK, Simpson FC. Investigational drugs for onychomycosis. Expert Opin Investig Drugs. 2014 Jan;23(1):97-106. doi: 10.1517/13543784.2013.840289. Epub 2013 Sep 26. Review. PubMed PMID: 24070182.

3: Ghannoum MA, Long L, Cirino AJ, Miller AR, Najafi R, Wang L, Sharma K, Anderson M, Memarzadeh B. Efficacy of NVC-422 in the treatment of dermatophytosis caused by Trichophyton mentagrophytes using a guinea pig model. Int J Dermatol. 2013 May;52(5):567-71. doi: 10.1111/j.1365-4632.2012.05477.x. PubMed PMID: 23590371.