STING Agonist 1a
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MedKoo CAT#: 463224

CAS#: 652142-94-4

Description: STING agonist 1a is an agonist of stimulator of interferon genes (STING). It induces expression of an IRF-inducible SEAP reporter gene in a cell-based assay. STING agonist 1a induces expression of IFN-β, IL-6, and chemokine ligand 10 in THP-1 cells, an effect that can be reversed by STING knockout or the STING inhibitor H-151.

Chemical Structure

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STING Agonist 1a
CAS# 652142-94-4
Instruction

Theoretical Analysis

MedKoo Cat#: 463224
Name: STING Agonist 1a
CAS#: 652142-94-4
Chemical Formula: C19H11Cl2N5O
Exact Mass: 395.03
Molecular Weight: 396.231
Elemental Analysis: C, 57.59; H, 2.80; Cl, 17.89; N, 17.68; O, 4.04

Price and Availability

Size Price Availability Quantity
25mg USD -2 2 Weeks
50mg USD -2 2 Weeks
100mg USD -2 2 Weeks
200mg USD -2 2 Weeks
500mg USD -2 2 Weeks
2g USD -2 2 Weeks
1mg USD 250 2 Weeks
5mg USD 580 2 Weeks
10mg USD 1000 2 Weeks
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Synonym: STING Agonist 1a; STING Agonist-1a;

IUPAC/Chemical Name: 4-chloro-1-(2-chloro-6-methoxyquinolin-3-yl)-[1,2,4]triazolo[4,3-a]quinoxaline

InChi Key: ABGPUQXRCXUIFE-UHFFFAOYSA-N

InChi Code: InChI=1S/C19H11Cl2N5O/c1-27-11-6-7-13-10(8-11)9-12(16(20)22-13)18-24-25-19-17(21)23-14-4-2-3-5-15(14)26(18)19/h2-9H,1H3

SMILES Code: ClC1=NC2=C(C=CC=C2)N3C1=NN=C3C4=C(N=C5C=CC(OC)=CC5=C4)Cl

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 396.23 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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