WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 574931

CAS#: 108923-79-1

Description: U0124 is an inactive analog of U0126.

Chemical Structure

CAS# 108923-79-1

Theoretical Analysis

MedKoo Cat#: 574931
Name: U0124
CAS#: 108923-79-1
Chemical Formula: C8H10N4S2
Exact Mass: 226.03
Molecular Weight: 226.320
Elemental Analysis: C, 42.46; H, 4.45; N, 24.76; S, 28.33

Price and Availability

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10mg USD 385 2 Weeks
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Synonym: U0124

IUPAC/Chemical Name: Bis[amino(methylthio)methylene]butanedinitrile


InChi Code: InChI=1S/C8H10N4S2/c1-13-7(11)5(3-9)6(4-10)8(12)14-2/h11-12H2,1-2H3/b7-5+,8-6+

SMILES Code: N#CC(/C(C#N)=C(N)/SC)=C(N)\SC

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 226.32 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1. Favata et al (1998) Identification of a novel inhibitor of mitogen-activated protein kinase kinase. J.Biol.Chem. 273 18623 PMID: 9660836

2. Fitzgerald (2000) Regulation of voltage-dependent calcium channels in rat sensory neurones involves a Ras-mitogen-activated protein kinase pathway. J.Physiol. 527 433 PMID: 10990531

3. Sekar et al (2001) Concerted transcriptional activation of the low density lipoprotein receptor gene by Ins and luteinizing hormone in cultured porcine granulosa-luteal cells: possible convergence of protein kinase A, phosphatidylinositol 3-kinase, and mitogen-activated pro Endocrinology 142 2921 PMID: 11416012