8-M-PDOT
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 471039

CAS#: 134865-70-6

Description: 8-M-PDOT is a selective melatonin receptor agonist


Chemical Structure

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8-M-PDOT
CAS# 134865-70-6

Theoretical Analysis

MedKoo Cat#: 471039
Name: 8-M-PDOT
CAS#: 134865-70-6
Chemical Formula: C14H19NO2
Exact Mass: 233.1416
Molecular Weight: 233.31
Elemental Analysis: C, 72.07; H, 8.21; N, 6.00; O, 13.71

Price and Availability

Size Price Availability Quantity
10.0mg USD 280.0 2 Weeks
25.0mg USD 510.0 2 Weeks
50.0mg USD 860.0 2 Weeks
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Synonym: AH 002, AH002, AH-002, 8-M-PDOT

IUPAC/Chemical Name: N-(8-methoxy-1,2,3,4-tetrahydronaphthalen-2-yl)propionamide

InChi Key: RVIGBTUDFAGRTQ-UHFFFAOYSA-N

InChi Code: InChI=1S/C14H19NO2/c1-3-14(16)15-11-8-7-10-5-4-6-13(17-2)12(10)9-11/h4-6,11H,3,7-9H2,1-2H3,(H,15,16)

SMILES Code: CCC(NC1CC2=C(C=CC=C2OC)CC1)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 233.31 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1. Noseda, A.C., Targa, A.D., Rodrigues, L.S., et al. REM sleep deprivation promotes a dopaminergic influence in the striatal MT2 anxiolytic-like effects. Sleep Sci. 9(1), 47-54 (2016).

2. Browning, C., Beresford, I., Fraser, N., et al. Pharmacological characterization of human recombinant melatonin mt1 and MT2 receptors. Br. J. Pharmacol. 129(5), 877-886 (2000).

3. Dubocovich ML, Masana MI, Iacob S, Sauri DM., Melatonin receptor antagonists that differentiate between the human Mel1a and Mel1b recombinant subtypes are used to assess the pharmacological profile of the rabbit retina ML1 presynaptic heteroreceptor., Naunyn Schmiedebergs Arch Pharmacol. 1997 Mar;355(3):365-75.

4. Dubocovich ML, Melatonin receptors: are there multiple subtypes? Trends Pharmacol Sci. 1995 Feb;16(2):50-6.

8-M-PDOT

10.0mg / USD 280.0