Navocaftor

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 558748

CAS#: 2159103-66-7

Description: Navocaftor is a cystic fibrosis transmembrane regulator (CFTR) and protein modulator.


Price and Availability

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Navocaftor is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 558748
Name: Navocaftor
CAS#: 2159103-66-7
Chemical Formula: C15H11F3N4O5S
Exact Mass: 416.0402
Molecular Weight: 416.33
Elemental Analysis: C, 43.27; H, 2.66; F, 13.69; N, 13.46; O, 19.21; S, 7.70


Synonym: Navocaftor

IUPAC/Chemical Name: (5-{3-amino-5-[4-(trifluoromethoxy)benzene-1-sulfonyl]pyridin-2-yl}-1,3,4-oxadiazol-2-yl)methanol

InChi Key: WOXOLLSAICIZNO-UHFFFAOYSA-N

InChi Code: InChI=1S/C15H11F3N4O5S/c16-15(17,18)27-8-1-3-9(4-2-8)28(24,25)10-5-11(19)13(20-6-10)14-22-21-12(7-23)26-14/h1-6,23H,7,19H2

SMILES Code: OCC1=NN=C(C2=NC=C(S(=O)(C3=CC=C(OC(F)(F)F)C=C3)=O)C=C2N)O1


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
2934.99.90.01