Damilen maleate

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 573859

CAS#: 30227-34-0

Description: Damilen maleate is the maleate salt of Amitriptyline --- a tricyclic antidepressant with anticholinergic and sedative properties.

Chemical Structure

Damilen maleate
CAS# 30227-34-0

Theoretical Analysis

MedKoo Cat#: 573859
Name: Damilen maleate
CAS#: 30227-34-0
Chemical Formula: C24H27NO4
Exact Mass: 393.194
Molecular Weight: 393.48
Elemental Analysis: C, 73.26; H, 6.92; N, 3.56; O, 16.26

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: Amitriptyline maleate, Damilen maleate

IUPAC/Chemical Name: 3-(10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-ylidene)-N,N-dimethylpropan-1-amine maleate


InChi Code: 1S/C20H23N.C4H4O4/c1-21(2)15-7-12-20-18-10-5-3-8-16(18)13-14-17-9-4-6-11-19(17)20;5-3(6)1-2-4(7)8/h3-6,8-12H,7,13-15H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1-

SMILES Code: CN(C)CCC=C1c2ccccc2CCc3ccccc13.OC(=O)\C=C/C(=O)O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 393.48 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Han FY, Kuo A, Nicholson JR, Corradinni L, Smith MT. Comparative Analgesic Efficacy of Pregabalin Administered According to Either a Prevention Protocol or an Intervention Protocol in Rats with Cisplatin-induced Peripheral Neuropathy. Clin Exp Pharmacol Physiol. 2018 May 21. doi: 10.1111/1440-1681.12971. [Epub ahead of print] PubMed PMID: 29781509.

2: Øiestad ÅML, Karinen R, Rogde S, Nilsen S, Boye Eldor KB, Brochmann GW, Arnestad M, Øiestad EL, Peres MD, Kristoffersen L, Vindenes V. Comparative Study of Postmortem Concentrations of Antidepressants in Several Different Matrices. J Anal Toxicol. 2018 May 14. doi: 10.1093/jat/bky030. [Epub ahead of print] PubMed PMID: 29762694.

3: Everitt H, Baldwin DS, Stuart B, Lipinska G, Mayers A, Malizia AL, Manson CC, Wilson S. Antidepressants for insomnia in adults. Cochrane Database Syst Rev. 2018 May 14;5:CD010753. doi: 10.1002/14651858.CD010753.pub2. [Epub ahead of print] Review. PubMed PMID: 29761479.