FH535-N

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 565755

CAS#: N/A

Description: FH535-N is a novel inhibitor of the wnt/β-catenin transcriptional activity, demonstrating significant increased rate of apoptosis in huh7 and plc/prf

Chemical Structure

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FH535-N
CAS# N/A
Instruction

Theoretical Analysis

MedKoo Cat#: 565755
Name: FH535-N
CAS#: N/A
Chemical Formula: C16H10Cl2N2O4S
Exact Mass: 395.97
Molecular Weight: 397.226
Elemental Analysis: C, 48.38; H, 2.54; Cl, 17.85; N, 7.05; O, 16.11; S, 8.07

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: FH535-N; FH535 N; FH535N

IUPAC/Chemical Name: 2,5-Dichloro-N-(4-nitronaphthalen-1-yl)benzenesulfonamide

InChi Key: VZBUNQNZGCGVOO-UHFFFAOYSA-N

InChi Code: InChI=1S/C16H10Cl2N2O4S/c17-10-5-6-13(18)16(9-10)25(23,24)19-14-7-8-15(20(21)22)12-4-2-1-3-11(12)14/h1-9,19H

SMILES Code: O=S(C1=CC(Cl)=CC=C1Cl)(NC2=C3C=CC=CC3=C([N+]([O-])=O)C=C2)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 397.23 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Turcios L, Chacon E, Garcia C, Eman P, Cornea V, Jiang J, Spear B, Liu C, Watt DS, Marti F, Gedaly R. Autophagic flux modulation by Wnt/β-catenin pathway inhibition in hepatocellular carcinoma. PLoS One. 2019 Feb 22;14(2):e0212538. doi: 10.1371/journal.pone.0212538. eCollection 2019. PubMed PMID: 30794613; PubMed Central PMCID: PMC6386480.