Formetanate hydrochloride

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 531416

CAS#: 23422-53-9

Description: Formetanate hydrochloride is a bioactive chemical.

Chemical Structure

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Formetanate hydrochloride
CAS# 23422-53-9
Instruction

Theoretical Analysis

MedKoo Cat#: 531416
Name: Formetanate hydrochloride
CAS#: 23422-53-9
Chemical Formula: C11H16ClN3O2
Exact Mass: 257.09
Molecular Weight: 257.718
Elemental Analysis: C, 51.27; H, 6.26; Cl, 13.76; N, 16.31; O, 12.42

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: Formetanate hydrochloride

IUPAC/Chemical Name: Carbamic acid, methyl-, ester with N'-(m-hydroxyphenyl)-N,N-dimethylformamidine, hydrochloride

InChi Key: MYPKGPZHHQEODQ-FNXZNAJJSA-N

InChi Code: InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H/b13-8+;

SMILES Code: CN(C)/C=N/C1=CC=CC(OC(NC)=O)=C1.[H]Cl

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 257.72 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Kobayashi M, Sakai N, Kamijo K, Koike H, Nemoto S, Shindo T. Determination of Formetanate Hydrochloride in Agricultural Products by LC-MS/MS. Shokuhin Eiseigaku Zasshi. 2017;58(5):221-228. doi: 10.3358/shokueishi.58.221. Japanese. PubMed PMID: 29081458.

2: Franco AA, Zanardi OZ, Jacob CRO, de Oliveira MBR, Yamamoto PT. Susceptibility of Euseius concordis (Mesostigmata: Phytoseiidae) to pesticides used in citrus production systems. Exp Appl Acarol. 2017 Sep;73(1):61-77. doi: 10.1007/s10493-017-0176-0. Epub 2017 Sep 2. PubMed PMID: 28866797.

3: Melnyk LJ, Wang Z, Li Z, Xue J. Prioritization of pesticides based on daily dietary exposure potential as determined from the SHEDS model. Food Chem Toxicol. 2016 Oct;96:167-73. doi: 10.1016/j.fct.2016.07.025. Epub 2016 Aug 4. PubMed PMID: 27497764.

4: Martins AC, Ribeiro FW, Zanatta G, Freire VN, Morais S, de Lima-Neto P, Correia AN. Modeling of laccase inhibition by formetanate pesticide using theoretical approaches. Bioelectrochemistry. 2016 Apr;108:46-53. doi: 10.1016/j.bioelechem.2015.12.004. Epub 2015 Dec 21. PubMed PMID: 26720841.

5: Oliveira TM, Barroso MF, Morais S, Araújo M, Freire C, de Lima-Neto P, Correia AN, Oliveira MB, Delerue-Matos C. Sensitive bi-enzymatic biosensor based on polyphenoloxidases-gold nanoparticles-chitosan hybrid film-graphene doped carbon paste electrode for carbamates detection. Bioelectrochemistry. 2014 Aug;98:20-9. doi: 10.1016/j.bioelechem.2014.02.003. Epub 2014 Mar 5. PubMed PMID: 24642204.

6: Ribeiro FW, Barroso MF, Morais S, Viswanathan S, de Lima-Neto P, Correia AN, Oliveira MB, Delerue-Matos C. Simple laccase-based biosensor for formetanate hydrochloride quantification in fruits. Bioelectrochemistry. 2014 Feb;95:7-14. doi: 10.1016/j.bioelechem.2013.09.005. Epub 2013 Oct 8. PubMed PMID: 24161938.

7: Nault BA, Shelton AM. Impact of insecticide efficacy on developing action thresholds for pest management: a case study of onion thrips (Thysanoptera: Thripidae) on onion. J Econ Entomol. 2010 Aug;103(4):1315-26. Erratum in: J Econ Entomol. 2010 Oct;103(5):v. PubMed PMID: 20857743.

8: Podhorniak LV, Kamel A, Rains DM. Determination of formetanate hydrochloride in fruit samples using liquid chromatography-mass selective detection or -tandem mass spectrometry. J Agric Food Chem. 2010 May 26;58(10):5862-7. doi: 10.1021/jf9038524. PubMed PMID: 20394429.

9: Divito CB, Davies S, Masoudi S, Muhoro CN. Relative stability of formamidine and carbamate groups in the bifunctional pesticide formetanate hydrochloride. J Agric Food Chem. 2007 Jul 11;55(14):5377-82. Epub 2007 Jun 7. PubMed PMID: 17552536.

10: Hardman JM, Franklin JL, Moreau DL, Bostanian NJ. An index for selective toxicity of miticides to phytophagous mites and their predators based on orchard trials. Pest Manag Sci. 2003 Dec;59(12):1321-32. PubMed PMID: 14667054.

11: Niemann RA. Determination of formetanate hydrochloride in selected fruits by coupled-column cation exchange liquid chromatography. J AOAC Int. 1993 Nov-Dec;76(6):1362-8. PubMed PMID: 8286975.

12: Khalaf KD, Sancenon J, de la Guardia M. Spectrophotometric flow injection determination of formetanate and m-aminophenol in water after reaction with p-aminophenol. Talanta. 1993 Aug;40(8):1173-81. PubMed PMID: 18965765.

13: Knowles CO. Metabolism of two acaricidal chemicals, N'-(4-chloro-o-tolyl)-N,N-dimethylformamidine (chlorphenamidine) and m-([(dimethylamino)methylene]amino)phenyl methylcarbamate hydrochloride (formetanate). J Agric Food Chem. 1970 Nov-Dec;18(6):1038-47. Review. PubMed PMID: 4921643.