LUF6283
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 471016

CAS#: 92933-48-7

Description: LUF6283 is a partial agonist of hydroxycarboxylic acid receptor 2

Chemical Structure

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LUF6283
CAS# 92933-48-7
Product data Instruction

Theoretical Analysis

MedKoo Cat#: 471016
Name: LUF6283
CAS#: 92933-48-7
Chemical Formula: C8H12N2O2
Exact Mass: 168.09
Molecular Weight: 168.196
Elemental Analysis: C, 57.13; H, 7.19; N, 16.66; O, 19.02

Price and Availability

Size Price Availability Quantity
5mg USD 300 2 weeks
10mg USD 550 2 weeks
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Synonym: LUF6283, LUF-6283, LUF 6283

IUPAC/Chemical Name: 5-butyl-1H-pyrazole-3-carboxylic acid

InChi Key: ZJTXSGLJNBAMJS-UHFFFAOYSA-N

InChi Code: InChI=1S/C8H12N2O2/c1-2-3-4-6-5-7(8(11)12)10-9-6/h5H,2-4H2,1H3,(H,9,10)(H,11,12)

SMILES Code: O=C(C1=NNC(CCCC)=C1)O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Product Data:
Product Data
Instruction:
View handling instruction
Biological target: LUF6283 is a potent and orally active HCA(2) partial agonist, with a Ki of 0.55 µM.
In vitro activity: TBD
In vivo activity: TBD

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 16.0 95.13
Ethanol 16.0 95.13

Preparing Stock Solutions

The following data is based on the product molecular weight 168.20 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol: TBD
In vitro protocol: TBD
In vivo protocol: TBD

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1. Li, Z., Blad, C.C., van der Sluis, R.J., et al. Effects of pyrazole partial agonists on HCA2-mediated flushing and VLDL-triglyceride levels in mice Br. J. Pharmacol. 167(4), 818-825 (2012).