OB-24 HCl
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 563722

CAS#: 939825-12-4

Description: OB-24 HCl is a potent and selective heme oxygenase 1 (HO-1) inhibitor.


Chemical Structure

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OB-24 HCl
CAS# 939825-12-4

Theoretical Analysis

MedKoo Cat#: 563722
Name: OB-24 HCl
CAS#: 939825-12-4
Chemical Formula: C15H18BrClN2O2
Exact Mass: 372.024
Molecular Weight: 373.67
Elemental Analysis: C, 48.21; H, 4.86; Br, 21.38; Cl, 9.49; N, 7.50; O, 8.56

Price and Availability

Size Price Availability Quantity
10.0mg USD 325.0 2 Weeks
50.0mg USD 1085.0 2 Weeks
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Synonym: OB-24 hydrochloride; OB-24 HCl; OB 24 HCl; OB24 HCl;

IUPAC/Chemical Name: 1-[[2-[2-(4-Bromophenyl)ethyl]-1,3-dioxolan-2-yl]methyl]-1H-imidazole hydrochloride

InChi Key: YSOWYXRHOAXXTG-UHFFFAOYSA-N

InChi Code: InChI=1S/C15H17BrN2O2.ClH/c16-14-3-1-13(2-4-14)5-6-15(19-9-10-20-15)11-18-8-7-17-12-18;/h1-4,7-8,12H,5-6,9-11H2;1H

SMILES Code: BrC1=CC=C(CCC2(CN3C=CN=C3)OCCO2)C=C1.[H]Cl

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

Preparing Stock Solutions

The following data is based on the product molecular weight 373.67 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Alaoui-Jamali MA, Bismar TA, Gupta A, Szarek WA, Su J, Song W, Xu Y, Xu B, Liu G, Vlahakis JZ, Roman G, Jiao J, Schipper HM. A novel experimental heme oxygenase-1-targeted therapy for hormone-refractory prostate cancer. Cancer Res. 2009 Oct 15;69(20):8017-24. doi: 10.1158/0008-5472.CAN-09-0419. Epub 2009 Oct 6. PubMed PMID: 19808972.

2: Gater D, Macauley D. American Chemical Society--238th National Meeting & Exposition. Developments in medicinal chemistry: part 2. 16-20 August 2009, Washington DC, USA. IDrugs. 2009 Oct;12(10):608-11. PubMed PMID: 19790005.