Chlorfenvinphos | CAS#470-90-6 | insecticide

Chlorfenvinphos
featured

WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 461782

CAS#: 470-90-6

Description: Chlorfenvinphos is an organophosphorous compound that possesses acaricidal and insecticidal properties.

Chemical Structure

Chlorfenvinphos

CAS# 470-90-6

Instruction

Theoretical Analysis

MedKoo Cat#: 461782
Name: Chlorfenvinphos
CAS#: 470-90-6
Chemical Formula: C12H14Cl3O4P
Exact Mass: 357.97
Molecular Weight: 359.560
Elemental Analysis: C, 40.09; H, 3.92; Cl, 29.58; O, 17.80; P, 8.61

Price and Availability

Size	Price	Availability	Quantity
250mg	USD 350	2 Weeks
Bulk inquiry Welcome, Customer: Please do not inquire quote if your intended use is for a patient since our products are for research use and for chemical synthesis use, not for human use . For in-stock products, we listed price in the web page. You may inquire prices for which sizes were not listed. If no price is listed, this means the product is not in stock at the moment, which may be available via custom synthesis. For cost-effective reason, minimum order of 1g is requested (typically very expensive). The lead time is usually 2-4 months. Quote of less than 1g will not be provided. MedKoo may not offer quote for below reasons: (1) current available synthetic method appears to be extremely expensive which is obviously not affordable to most customers; (2) Key raw material to make the product is temporally not available; (3) DEA controlled substances; (4) the product is under patent protection in customer’s country.

Synonym: Chlorfenvinphos; Birlan; C 8949; C-8949; C8949; Clofenvinfosum; Dermaton; Enolofos; Haptasol; Sapecron; SD 4072; SD-4072; SD4072; SD 7859; SD-7859; SD7859;

IUPAC/Chemical Name: (E)-2-chloro-1-(2,4-dichlorophenyl)vinyl diethyl phosphate

InChi Key: FSAVDKDHPDSCTO-XYOKQWHBSA-N

InChi Code: InChI=1S/C12H14Cl3O4P/c1-3-17-20(16,18-4-2)19-12(8-13)10-6-5-9(14)7-11(10)15/h5-8H,3-4H2,1-2H3/b12-8+

SMILES Code: O=P(OCC)(O/C(C1=CC=C(Cl)C=C1Cl)=C/Cl)OCC

Appearance: To be determined

Purity: >96% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

More Info:

Instruction:

View handling instruction

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 359.56 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

Formulation protocol:
In vitro protocol:
In vivo protocol:

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

Mass

Concentration

Volume

M. Wt* g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Concentration 1

Volume 1

Concentration 2

Volume 2

1: Sosnowska B, Huras B, Krokosz A, Bukowska B. The effect of bromfenvinphos, its impurities and chlorfenvinphos on acetylcholinesterase activity. Int J Biol Macromol. 2013 Jun;57:38-44. doi: 10.1016/j.ijbiomac.2013.02.011. Epub 2013 Mar 7. PubMed PMID: 23474396.

2: Roszczenko A, Rogalska J, Moniuszko-Jakoniuk J, Brzóska MM. The effect of exposure to chlorfenvinphos on lipid metabolism and apoptotic and necrotic cells death in the brain of rats. Exp Toxicol Pathol. 2013 Jul;65(5):531-9. doi: 10.1016/j.etp.2012.03.002. Epub 2012 Apr 10. PubMed PMID: 22498023.

3: Mutebi F, von Samson-Himmelstjerna G, Feldmeier H, Waiswa C, Bukeka Muhindo J, Krücken J. Successful Treatment of Severe Tungiasis in Pigs Using a Topical Aerosol Containing Chlorfenvinphos, Dichlorphos and Gentian Violet. PLoS Negl Trop Dis. 2016 Oct 11;10(10):e0005056. doi: 10.1371/journal.pntd.0005056. eCollection 2016 Oct. PubMed PMID: 27727268; PubMed Central PMCID: PMC5058476.

4: Łukaszewicz-Hussain A. [Liver and serum glutathione concentration and liver hydrogen peroxide in rats subchronically intoxicated with chlorfenvinphos--organophosphate insecticide]. Med Pr. 2011;62(1):23-9. Polish. PubMed PMID: 21748880.

5: Mahdy FM, El-Maghraby SI. Effect of processing on 14C-chlorfenvinphos residues in maize oil and bioavailability of its cake residues on rats. Bull Environ Contam Toxicol. 2010 May;84(5):582-6. doi: 10.1007/s00128-010-9984-1. Epub 2010 Apr 20. PubMed PMID: 20405102.

6: Martínez MA, Ballesteros S. Two suicidal fatalities due to the ingestion of chlorfenvinphos formulations: simultaneous determination of the pesticide and the petroleum distillates in tissues by gas chromatography-flame-ionization detection and gas chromatography-mass spectrometry. J Anal Toxicol. 2012 Jan-Feb;36(1):44-51. doi: 10.1093/jat/bkr014. PubMed PMID: 22290752.

7: Alix A, Cortesero AM, Nénon JP, Anger JP. Selectivity assessment of chlorfenvinphos reevaluated by including physiological and behavioral effects on an important beneficial insect. Environ Toxicol Chem. 2001 Nov;20(11):2530-6. PubMed PMID: 11699779.

8: Raszewski G, Filip R. Correlation of therapeutic effect of obidoxime and dosing time in the acute intoxication by chlorfenvinphos in rats. Basic Clin Pharmacol Toxicol. 2009 Jul;105(1):37-45. doi: 10.1111/j.1742-7843.2009.00398.x. Epub 2009 Apr 3. PubMed PMID: 19371264.

9: Sosnowska B, Huras B, Bukowska B. Oxidative stress in human erythrocytes treated with bromfenvinphos and its impurities. Pestic Biochem Physiol. 2015 Feb;118:43-9. doi: 10.1016/j.pestbp.2014.11.009. Epub 2014 Nov 26. PubMed PMID: 25752429.

10: Sismeiro-Vivas J, Abrantes N, Pereira JL, Castro BB, Gonçalves F. Short-term effects of Quirlan (chlorfenvinphos) on the behavior and acetylcholinesterase activity of Gambusia holbrooki. Environ Toxicol. 2007 Apr;22(2):194-202. PubMed PMID: 17366566.

11: Kamiński M, Wiaderkiewicz R, Siekierska E. Effect of chlorfenvinphos on rat liver subjected to ischemia and reperfusion. Przegl Lek. 1997;54(10):693-701. PubMed PMID: 9478088.

12: Sedrowicz L, Witkowska D, Oledzka R. Effect of chlorfenvinphos, cypermethrin and their mixture on the intestinal transport of leucine and methionine. J Appl Toxicol. 1996 Nov-Dec;16(6):483-9. PubMed PMID: 8956093.

13: Bailey HC, Elphick JR, Krassoi R, Mulhall AM, Lovell AJ, Slee DJ. Identification of chlorfenvinphos toxicity in a municipal effluent in Sydney, New South Wales, Australia. Environ Toxicol Chem. 2005 Jul;24(7):1773-8. PubMed PMID: 16050596.

14: Nunes B, Barbosa AR, Antunes SC, Gonçalves F. Combination effects of anticholinesterasics in acetylcholinesterase of a fish species: effects of a metallic compound, an organophosphate pesticide, and a pharmaceutical drug. Environ Sci Pollut Res Int. 2014 May;21(9):6258-62. doi: 10.1007/s11356-014-2584-6. Epub 2014 Feb 19. PubMed PMID: 24535665.

15: Rodrigues S, Correia AT, Antunes SC, Nunes B. Alterations in gills of Lepomis gibbosus, after acute exposure to several xenobiotics (pesticide, detergent and pharmaceuticals): morphometric and biochemical evaluation. Drug Chem Toxicol. 2015 Apr;38(2):126-32. doi: 10.3109/01480545.2014.918999. Epub 2014 May 21. PubMed PMID: 24844684.

16: Mdegela RH, Mosha RD, Sandvik M, Skaare JU. Assessment of acetylcholinesterase activity in Clarias gariepinus as a biomarker of organophosphate and carbamate exposure. Ecotoxicology. 2010 Jun;19(5):855-63. doi: 10.1007/s10646-010-0466-3. Epub 2010 Feb 19. PubMed PMID: 20169407.

17: Hartnik T, Styrishave B. Impact of biotransformation and bioavailability on the toxicity of the insecticides alpha-cypermethrin and chlorfenvinphos in earthworm. J Agric Food Chem. 2008 Nov 26;56(22):11057-64. doi: 10.1021/jf8017904. PubMed PMID: 18959415.

18: Mohapatra PK, Schiewer U. Effect of dimethoate and chlorfenvinphos on plasma membrane integrity of Synechocystis sp. PCC 6803. Ecotoxicol Environ Saf. 1998 Nov;41(3):269-74. PubMed PMID: 9799578.

19: Serrano R, López FJ, Hernández F, Peña JB. Bioconcentration of chlorpyrifos, chlorfenvinphos, and methidathion in Mytilus galloprovincialis. Bull Environ Contam Toxicol. 1997 Dec;59(6):968-75. PubMed PMID: 9400670.

20: Ikeda T, Yoshida M, Iwasaki M, Tsuda S, Shirasu Y. Effects of temperature during exposure on inhalation toxicities of chlorfenvinphos and fenthion in rats. Nihon Juigaku Zasshi. 1987 Oct;49(5):929-31. PubMed PMID: 3682534.

Your view history

Chlorfenvinphos featured