Sulfabromomethazine
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MedKoo CAT#: 461673

CAS#: 116-45-0

Description: Sulfabromomethazine, also known as Bromosulfamethazine, NSC 5874, SN 3517, is a long-acting derivative of sulfamezathine that is used in the poultry, swine and cattle industries for the treatment of coccidiosis.


Price and Availability

Size Price Shipping out time Quantity
10mg USD 150 Same day
25mg USD 250 Same day
50mg USD 450 Same day
100mg USD 850 Same day
200mg USD 1650 Same day
Inquire bulk and customized quantity

Pricing updated 2020-10-24. Prices are subject to change without notice.

Sulfabromomethazine, purity > 98%, is in stock. The same day shipping out after order is received.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 461673
Name: Sulfabromomethazine
CAS#: 116-45-0
Chemical Formula: C12H13BrN4O2S
Exact Mass: 355.9943
Molecular Weight: 357.22
Elemental Analysis: C, 40.35; H, 3.67; Br, 22.37; N, 15.68; O, 8.96; S, 8.97


Synonym: 5-Bromosulfamethazine; Bromosulfamethazine; NSC 5874; NSC-5874; NSC5874; SN 3517; SN-3517; SN3517; Sulfabrom ; Sulfabromomethazine;

IUPAC/Chemical Name: 4-amino-N-(5-bromo-4,6-dimethylpyrimidin-2-yl)benzenesulfonamide

InChi Key: KWXCNODTHBHSIQ-UHFFFAOYSA-N

InChi Code: InChI=1S/C12H13BrN4O2S/c1-7-11(13)8(2)16-12(15-7)17-20(18,19)10-5-3-9(14)4-6-10/h3-6H,14H2,1-2H3,(H,15,16,17)

SMILES Code: O=S(C1=CC=C(N)C=C1)(NC2=NC(C)=C(Br)C(C)=N2)=O


Technical Data

Appearance:
Orange to light red solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Certificate of Analysis:

Safety Data Sheet (SDS):

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in 1M sodium hydroxide, soluble in acetic acid, slightly soluble in DMSO and ethanol, not soluble in water.

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.9001


References

1: STOWE CM, ARONSON AL, JOHNSON K. The pharmacology of sulfabromomethazine, a new long-acting sulfonamide, in cattle. Am J Vet Res. 1958 Apr;19(71):345-53. PubMed PMID: 13533757.

2: Unruh J, Schwartz DP, Barford RA. Quantitation of sulfamethazine in pork tissue by thin-layer chromatography. J AOAC Int. 1993 Mar-Apr;76(2):335-41. PubMed PMID: 8471859.

3: Goodspeed DP, Simpson RM, Ashworth RB, Shafer JW, Cook HR. Sensitive and specific gas-liquid chromatographic-spectrophotometric screening procedure for trace levels of five sulfonamides in liver, kidney, and muscle tissue. J Assoc Off Anal Chem. 1978 Sep;61(5):1050-3. PubMed PMID: 721719.

4: Fink DW, Martin RP, Blodinger J. Facile separation of sulfonamides from their degradates by liquid--liquid extraction. J Pharm Sci. 1978 Oct;67(10):1415-9. PubMed PMID: 702292.

5: Thomas MH, Soroka KE, Thomas SH. Quantitative thin layer chromatographic multi-sulfonamide screening procedure. J Assoc Off Anal Chem. 1983 Jul;66(4):881-3. PubMed PMID: 6885694.

6: Manuel AJ, Steller WA. Gas-liquid chromatographic determination of sulfamethazine in swine and cattle tissues. J Assoc Off Anal Chem. 1981 Jul;64(4):794-9. PubMed PMID: 7275892.