Urechistachykinin I

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 598679

CAS#: 149097-03-0

Description: Urechistachykinin I is a novel tachykinin-related peptide receptor isolated from the echiuroid worm Urechis unicinctus.

Chemical Structure

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Urechistachykinin I
CAS# 149097-03-0
Instruction

Theoretical Analysis

MedKoo Cat#: 598679
Name: Urechistachykinin I
CAS#: 149097-03-0
Chemical Formula: C50H85N19O14
Exact Mass: 1,175.65
Molecular Weight: 1,176.340
Elemental Analysis: C, 51.05; H, 7.28; N, 22.62; O, 19.04

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: Urechistachykinin I; H-Leu-arg-gln-ser-gln-phe-val-gly-ser-arg-NH2;

IUPAC/Chemical Name: (S)-2-((S)-2-((S)-5-amino-2-((S)-2-((S)-2-amino-4-methylpentanamido)-5-guanidinopentanamido)-5-oxopentanamido)-3-hydroxypropanamido)-N1-((6S,9S,15S,18S)-1-amino-6-carbamoyl-9-(hydroxymethyl)-1-imino-15-isopropyl-8,11,14,17-tetraoxo-19-phenyl-2,7,10,13,16-pentaazanonadecan-18-yl)pentanediamide

InChi Key: MXFCWEFJWLZUIJ-RAUUPGJSSA-N

InChi Code: InChI=1S/C50H85N19O14/c1-25(2)20-28(51)41(76)64-30(13-9-19-60-50(57)58)42(77)65-32(15-17-37(53)73)44(79)68-35(24-71)47(82)66-31(14-16-36(52)72)43(78)67-33(21-27-10-6-5-7-11-27)45(80)69-39(26(3)4)48(83)61-22-38(74)62-34(23-70)46(81)63-29(40(54)75)12-8-18-59-49(55)56/h5-7,10-11,25-26,28-35,39,70-71H,8-9,12-24,51H2,1-4H3,(H2,52,72)(H2,53,73)(H2,54,75)(H,61,83)(H,62,74)(H,63,81)(H,64,76)(H,65,77)(H,66,82)(H,67,78)(H,68,79)(H,69,80)(H4,55,56,59)(H4,57,58,60)/t28-,29-,30-,31-,32-,33-,34-,35-,39-/m0/s1

SMILES Code: N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCC(N)=O)C(N[C@@H](CO)C(N[C@@H](CCC(N)=O)C(N[C@@H](Cc1ccccc1)C(N[C@@H](C(C)C)C(NCC(N[C@@H](CO)C(N[C@@H](CCCNC(N)=N)C(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 1,176.34 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Sung WS, Lee J, Cho J, Lee DG. The functional role of the tachykinin consensus region of urechistachykinin peptide family for its antimicrobial activity. Biol Pharm Bull. 2011;34(6):921-4. PubMed PMID: 21628896.

2: Ikeda T, Minakata H, Nomoto K, Kubota I, Muneoka Y. Two novel tachykinin-related neuropeptides in the echiuroid worm, Urechis unicinctus. Biochem Biophys Res Commun. 1993 Apr 15;192(1):1-6. PubMed PMID: 8476410.

3: Kawada T, Masuda K, Satake H, Minakata H, Muneoka Y, Nomoto K. Identification of multiple urechistachykinin peptides, gene expression, pharmacological activity, and detection using mass spectrometric analyses. Peptides. 2000 Dec;21(12):1777-83. PubMed PMID: 11150637.

4: Kawada T, Satake H, Minakata H, Muneoka Y, Nomoto K. Characterization of a novel cDNA sequence encoding invertebrate tachykinin-related peptides isolated from the echiuroid worm, Urechis unicinctus. Biochem Biophys Res Commun. 1999 Oct 5;263(3):848-52. PubMed PMID: 10512769.

5: Sung WS, Park SH, Lee DG. Antimicrobial effect and membrane-active mechanism of Urechistachykinins, neuropeptides derived from Urechis unicinctus. FEBS Lett. 2008 Jul 9;582(16):2463-6. doi: 10.1016/j.febslet.2008.06.015. Epub 2008 Jun 18. PubMed PMID: 18570895.

6: Ikeda T, Minakata H, Nomoto K. The importance of C-terminal residues of vertebrate and invertebrate tachykinins for their contractile activities in gut tissues. FEBS Lett. 1999 Nov 19;461(3):201-4. PubMed PMID: 10567697.