AH 6696

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 591417

CAS#: 6722-09-4

Description: AH 6696 is a biochemical.

Chemical Structure

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AH 6696
CAS# 6722-09-4
Instruction

Theoretical Analysis

MedKoo Cat#: 591417
Name: AH 6696
CAS#: 6722-09-4
Chemical Formula: C12H9NO2
Exact Mass: 199.06
Molecular Weight: 199.210
Elemental Analysis: C, 72.35; H, 4.55; N, 7.03; O, 16.06

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: AH 6696; AH-6696; AH6696

IUPAC/Chemical Name: 5H-(1)Benzopyrano(2,3-b)pyridin-5-ol

InChi Key: CAOGEKWDLGLKQK-UHFFFAOYSA-N

InChi Code: InChI=1S/C12H9NO2/c14-11-8-4-1-2-6-10(8)15-12-9(11)5-3-7-13-12/h1-7,11,14H

SMILES Code: OC1C2=CC=CC=C2OC3=NC=CC=C31

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 199.21 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Zuckerman V, Sokolov E, Swet JH, Ahrens WA, Showlater V, Iannitti DA, Mckillop IH. Expression and function of lysophosphatidic acid receptors (LPARs) 1 and 3 in human hepatic cancer progenitor cells. Oncotarget. 2016 Jan 19;7(3):2951-67. doi: 10.18632/oncotarget.6696. PubMed PMID: 26701886; PubMed Central PMCID: PMC4823083.

2: Zorzi M, Senore C, Turrin A, Mantellini P, Visioli CB, Naldoni C, Sassoli De' Bianchi P, Fedato C, Anghinoni E, Zappa M, Hassan C; Italian colorectal cancer screening survey group. Appropriateness of endoscopic surveillance recommendations in organised colorectal cancer screening programmes based on the faecal immunochemical test. Gut. 2016 Nov;65(11):1822-1828. doi: 10.1136/gutjnl-2015-310139. Epub 2015 Aug 21. PubMed PMID: 26297727.

3: Fujii T, Ota M, Hori H, Hattori K, Teraishi T, Matsuo J, Kinoshita Y, Ishida I, Nagashima A, Kunugi H. The common functional FKBP5 variant rs1360780 is associated with altered cognitive function in aged individuals. Sci Rep. 2014 Oct 21;4:6696. doi: 10.1038/srep06696. PubMed PMID: 25331639; PubMed Central PMCID: PMC4204028.

4: Morton AM, Sefik E, Upadhyay R, Weissleder R, Benoist C, Mathis D. Endoscopic photoconversion reveals unexpectedly broad leukocyte trafficking to and from the gut. Proc Natl Acad Sci U S A. 2014 May 6;111(18):6696-701. doi: 10.1073/pnas.1405634111. Epub 2014 Apr 21. PubMed PMID: 24753589; PubMed Central PMCID: PMC4020091.

5: Xu X, Jerskey BA, Cote DM, Walsh EG, Hassenstab JJ, Ladino ME, Clark US, Labbe DR, Gunstad JJ, Poppas A, Cohen RA, Hoge RD, Sweet LH. Cerebrovascular perfusion among older adults is moderated by strength training and gender. Neurosci Lett. 2014 Feb 7;560:26-30. doi: 10.1016/j.neulet.2013.12.011. Epub 2013 Dec 17. PubMed PMID: 24355360; PubMed Central PMCID: PMC3920729.

6: Hutchinson KE, Lipson D, Stephens PJ, Otto G, Lehmann BD, Lyle PL, Vnencak-Jones CL, Ross JS, Pietenpol JA, Sosman JA, Puzanov I, Miller VA, Pao W. BRAF fusions define a distinct molecular subset of melanomas with potential sensitivity to MEK inhibition. Clin Cancer Res. 2013 Dec 15;19(24):6696-702. doi: 10.1158/1078-0432.CCR-13-1746. PubMed PMID: 24345920; PubMed Central PMCID: PMC3880773.

7: Martinez CH, Williams AK, Chin JL, Stitt L, Izawa JI. Perineural invasion and TRUS findings are complementary in predicting prostate cancer biology. Can J Urol. 2013 Apr;20(2):6696-701. PubMed PMID: 23587509.

8: Wu B, Sahoo D, Brooks JD. Comprehensive gene expression changes associated with mouse postnatal kidney development. J Urol. 2013 Jun;189(6):2385-90. doi: 10.1016/j.juro.2012.12.002. Epub 2012 Dec 5. PubMed PMID: 23220383.

9: Vermaat JS, Nijman IJ, Koudijs MJ, Gerritse FL, Scherer SJ, Mokry M, Roessingh WM, Lansu N, de Bruijn E, van Hillegersberg R, van Diest PJ, Cuppen E, Voest EE. Primary colorectal cancers and their subsequent hepatic metastases are genetically different: implications for selection of patients for targeted treatment. Clin Cancer Res. 2012 Feb 1;18(3):688-99. doi: 10.1158/1078-0432.CCR-11-1965. Epub 2011 Dec 15. PubMed PMID: 22173549.

10: Arora SK, Dey P. Fractal and lacunar dimension of the chorionic villi of molar pregnancy. Anal Quant Cytol Histol. 2011 Apr;33(2):82-4. PubMed PMID: 21980610.

11: Tan H, Wang M, Yang CT, Pant S, Bhakoo KK, Wong SY, Chen ZK, Li X, Wang J. Silica nanocapsules of fluorescent conjugated polymers and superparamagnetic nanocrystals for dual-mode cellular imaging. Chemistry. 2011 Jun 6;17(24):6696-706. doi: 10.1002/chem.201003632. Epub 2011 May 3. PubMed PMID: 21542037.

12: Kolo ES, Salisu AD, Tabari AM, Dahilo EA, Aluko AA. Plain radiographic evaluation of the nasopharynx: do raters agree? Int J Pediatr Otorhinolaryngol. 2010 May;74(5):532-4. doi: 10.1016/j.ijporl.2010.02.015. Epub 2010 Mar 12. PubMed PMID: 20227115.

13: Fukuda MN, Sugihara K, Nakayama J. Trophinin: what embryo implantation teaches us about human cancer. Cancer Biol Ther. 2008 Aug;7(8):1165. Review. PubMed PMID: 18769125.

14: Bilimoria KY, Bentrem DJ, Ko CY, Stewart AK, Winchester DP, Talamonti MS, Halverson AL. Squamous cell carcinoma of the anal canal: utilization and outcomes of recommended treatment in the United States. Ann Surg Oncol. 2008 Jul;15(7):1948-58. doi: 10.1245/s10434-008-9905-2. Epub 2008 Apr 15. PubMed PMID: 18414951.

15: Iten F, Müller B, Schindler C, Rochlitz C, Oertli D, Mäcke HR, Müller-Brand J, Walter MA. Response to [90Yttrium-DOTA]-TOC treatment is associated with long-term survival benefit in metastasized medullary thyroid cancer: a phase II clinical trial. Clin Cancer Res. 2007 Nov 15;13(22 Pt 1):6696-702. PubMed PMID: 18006770.

16: Gumireddy K, Sun F, Klein-Szanto AJ, Gibbins JM, Gimotty PA, Saunders AJ, Schultz PG, Huang Q. In vivo selection for metastasis promoting genes in the mouse. Proc Natl Acad Sci U S A. 2007 Apr 17;104(16):6696-701. Epub 2007 Apr 9. PubMed PMID: 17420453; PubMed Central PMCID: PMC1871848.

17: McCool KW, Xu X, Singer DB, Murdoch FE, Fritsch MK. The role of histone acetylation in regulating early gene expression patterns during early embryonic stem cell differentiation. J Biol Chem. 2007 Mar 2;282(9):6696-706. Epub 2007 Jan 4. PubMed PMID: 17204470.

18: Querzoli P, Pedriali M, Rinaldi R, Lombardi AR, Biganzoli E, Boracchi P, Ferretti S, Frasson C, Zanella C, Ghisellini S, Ambrogi F, Antolini L, Piantelli M, Iacobelli S, Marubini E, Alberti S, Nenci I. Axillary lymph node nanometastases are prognostic factors for disease-free survival and metastatic relapse in breast cancer patients. Clin Cancer Res. 2006 Nov 15;12(22):6696-701. PubMed PMID: 17121888.

19: Saxe R, Powell LJ. It's the thought that counts: specific brain regions for one component of theory of mind. Psychol Sci. 2006 Aug;17(8):692-9. PubMed PMID: 16913952.

20: Lin B, Jakobs TC, Masland RH. Different functional types of bipolar cells use different gap-junctional proteins. J Neurosci. 2005 Jul 13;25(28):6696-701. PubMed PMID: 16014731.