WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 596537
Description: L 368935 is a cholecystokinin receptor antagonist.
MedKoo Cat#: 596537
Name: L 368935
Chemical Formula: C27H26N8O2
Exact Mass: 494.2179
Molecular Weight: 494.55
Elemental Analysis: C, 65.57; H, 5.30; N, 22.66; O, 6.47
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.
Synonym: L 368935; L-368935; L368935; L-368,935; L 368,935; L368,935;
IUPAC/Chemical Name: (R)-1-(3-(1H-tetrazol-5-yl)phenyl)-3-(1-isobutyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)urea
InChi Key: WOEBZQREQISGPC-VWLOTQADSA-N
InChi Code: InChI=1S/C27H26N8O2/c1-17(2)16-35-22-14-7-6-13-21(22)23(18-9-4-3-5-10-18)29-25(26(35)36)30-27(37)28-20-12-8-11-19(15-20)24-31-33-34-32-24/h3-15,17,25H,16H2,1-2H3,(H2,28,30,37)(H,31,32,33,34)/t25-/m0/s1
SMILES Code: O=C(NC1=CC=CC(C2=NN=NN2)=C1)N[C@H]3C(N(CC(C)C)C4=CC=CC=C4C(C5=CC=CC=C5)=N3)=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 494.55 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Patel S, Chapman KL, Smith AJ, Heald A, Freedman SB. Use of ex vivo binding to estimate brain penetration and central activity of CCK-B antagonists. Ann N Y Acad Sci. 1994 Mar 23;713:360-3. PubMed PMID: 8185188.
2: Pedersen K, Nielsen FC, Rehfeld JF. Regulation of the human cholecystokinin gene. Ann N Y Acad Sci. 1994 Mar 23;713:321-3. PubMed PMID: 8185176.
3: Patel S, Chapman KL, Heald A, Smith AJ, Freedman SB. Measurement of central nervous system activity of systemically administered CCKB receptor antagonists by ex vivo binding. Eur J Pharmacol. 1994 Mar 3;253(3):237-44. PubMed PMID: 8200418.