Dienone B

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 591259

CAS#: 17194-81-9

Description: Dienone B is a cytotoxic secondary metabolite from tyrosine as isolated from the sponges Verongia aerophoba & Aplysina aerophoba.

Chemical Structure

img
Dienone B
CAS# 17194-81-9
Instruction

Theoretical Analysis

MedKoo Cat#: 591259
Name: Dienone B
CAS#: 17194-81-9
Chemical Formula: C8H7Br2NO3
Exact Mass: 322.88
Molecular Weight: 324.960
Elemental Analysis: C, 29.57; H, 2.17; Br, 49.18; N, 4.31; O, 14.77

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: Dienone B; NSC 289074; NSC-289074; NSC289074

IUPAC/Chemical Name: 2,5-Cyclohexadiene-1-acetamide, 3,5-dibromo-1-hydroxy-4-oxo-

InChi Key: OPJJYFWUWHEWDE-UHFFFAOYSA-N

InChi Code: InChI=1S/C8H7Br2NO3/c9-4-1-8(14,3-6(11)12)2-5(10)7(4)13/h1-2,14H,3H2,(H2,11,12)

SMILES Code: O=C(N)CC1(O)C=C(Br)C(C(Br)=C1)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 324.96 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

1: Koulman A, Proksch P, Ebel R, Beekman AC, van Uden W, Konings AW, Pedersen JA, Pras N, Woerdenbag HJ. Cytotoxicity and mode of action of aeroplysinin-1 and a related dienonefrom the sponge Aplysina aerophoba. J Nat Prod. 1996 Jun;59(6):591-4. PubMed PMID: 8786366.

2: Kreuter MH, Robitzki A, Chang S, Steffen R, Michaelis M, Kljajić Z, Bachmann M, Schröder HC, Müller WE. Production of the cytostatic agent aeroplysinin by the sponge Verongia aerophoba in in vitro culture. Comp Biochem Physiol C. 1992;101(1):183-7. PubMed PMID: 1350964.

3: Gorshkova IA, Gorshkov BA, Makar'eva TN, Stonik VA, Zamaraeva MV. [Characteristics of the inhibiting action of dienone B on adenosine triphosphatase activity]. Izv Akad Nauk SSSR Biol. 1988 Sep-Oct;(5):676-82. Russian. PubMed PMID: 2849614.