WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 581196

CAS#: 110298-64-1

Description: Dactylocycline is novel tetracycline derivatives produced by a Dactylosporangium sp. the aglycone was cross resistant with tetracycline, the dactylocyclines proved active against certain tetracycline-resistant organisms.

Chemical Structure

CAS# 110298-64-1

Theoretical Analysis

MedKoo Cat#: 581196
Name: Dactylocyclinone
CAS#: 110298-64-1
Chemical Formula: C22H23ClN2O10
Exact Mass: 510.1041
Molecular Weight: 510.88
Elemental Analysis: C, 51.72; H, 4.54; Cl, 6.94; N, 5.48; O, 31.32

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: Dactylocyclinone; Sch 34164;

IUPAC/Chemical Name: 2-Naphthacenecarboxamide, 1,4,4a,5,5a,6,11,12a-octahydro-7-chloro-4-(dimethylamino)-1,11-dioxo-3,4a,6,10,12,12a-hexahydroxy-8-methoxy-, (4R-(4-alpha,4a-alpha,5a-alpha,6-beta,12-alpha))-


InChi Code: InChI=1S/C22H23ClN2O10/c1-25(2)17-16(29)12(20(24)32)19(31)22(34)18(30)9-6(5-21(17,22)33)14(27)11-10(15(9)28)7(26)4-8(35-3)13(11)23/h4,6,14,17,26-27,29-30,33-34H,5H2,1-3H3,(H2,24,32)/t6-,14-,17+,21+,22?/m0/s1

SMILES Code: O=C(C(C1=O)=C(O)[C@@H](N(C)C)[C@]2(O)C[C@]3([H])[C@H](O)C4=C(C(C3=C(O)C21O)=O)C(O)=CC(OC)=C4Cl)N

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 510.88 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Devasthale PV, Mitscher LA, Telikepalli H, Vander Velde D, Zou JY, Ax HA, Tymiak AA. Dactylocyclines, novel tetracycline derivatives produced by a Dactylosporangium sp. III. Absolute stereochemistry of the dactylocyclines. J Antibiot (Tokyo). 1992 Dec;45(12):1907-13. PubMed PMID: 1490882.

2: Cacciapuoti A, Moss EL Jr, Menzel F Jr, Cramer CA, Weiss W, Loebenberg D, Hare RS, Miller GH. In vitro and in vivo characterization of novel 8-methoxy derivatives of chlortetracycline. J Antibiot (Tokyo). 1987 Oct;40(10):1426-30. PubMed PMID: 3680008.

3: Tymiak AA, Ax HA, Bolgar MS, Kahle AD, Porubcan MA, Andersen NH. Dactylocyclines, novel tetracycline derivatives produced by a Dactylosporangium sp. II. Structure elucidation. J Antibiot (Tokyo). 1992 Dec;45(12):1899-906. PubMed PMID: 1490881.

4: Patel M, Gullo VP, Hegde VR, Horan AC, Marquez JA, Vaughan R, Puar MS, Miller GH. A new tetracycline antibiotic from a Dactylosporangium species. Fermentation, isolation and structure elucidation. J Antibiot (Tokyo). 1987 Oct;40(10):1414-8. PubMed PMID: 3680006.