Toxoflavin
featured

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 562222

CAS#: 84-82-2

Description: PKF118-310 is a WNT-signaling modulator. It acts by antagonizing Tcf4/β-catenin signaling, and inhibiting the Notch pathway.

Chemical Structure

img
Toxoflavin
CAS# 84-82-2
Instruction

Theoretical Analysis

MedKoo Cat#: 562222
Name: Toxoflavin
CAS#: 84-82-2
Chemical Formula: C7H7N5O2
Exact Mass: 193.06
Molecular Weight: 193.166
Elemental Analysis: C, 43.53; H, 3.65; N, 36.26; O, 16.57

Price and Availability

Size Price Availability Quantity
5mg USD 260
10mg USD 460
Bulk inquiry

Synonym: PKF118-310; PKF118 310; PKF118310; Toxoflavin; Xanthothricin;

IUPAC/Chemical Name: 1,6-Dimethyl-pyrimido[5,4-e]-1,2,4-triazine-5,7(1H,6H)-dione

InChi Key: SLGRAIAQIAUZAQ-UHFFFAOYSA-N

InChi Code: InChI=1S/C7H7N5O2/c1-11-6(13)4-5(10-7(11)14)12(2)9-3-8-4/h3H,1-2H3

SMILES Code: O=C(C1=NC=NN(C)C1=N2)N(C)C2=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 193.17 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

1: Chen G, Xie L, Liu BR. [Stem cell-targeted therapy--a new strategy for cancer treatment]. Zhonghua Zhong Liu Za Zhi. 2008 Nov;30(11):801-3. Review. Chinese. PubMed PMID: 19173821.

2: Katoh M, Katoh M. WNT signaling pathway and stem cell signaling network. Clin Cancer Res. 2007 Jul 15;13(14):4042-5. Review. PubMed PMID: 17634527.