Tiemonium iodide

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 562202

CAS#: 6252-92-2

Description: Tiemonium iodide is a muscarinic receptor antagonist, an anticholinergic, and a parasympatholytic.

Chemical Structure

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Tiemonium iodide
CAS# 6252-92-2
Instruction

Theoretical Analysis

MedKoo Cat#: 562202
Name: Tiemonium iodide
CAS#: 6252-92-2
Chemical Formula: C18H24INO2S
Exact Mass: 445.06
Molecular Weight: 445.350
Elemental Analysis: C, 48.54; H, 5.43; I, 28.49; N, 3.15; O, 7.18; S, 7.20

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: Tiemonium iodide; Visceralgine; Visceralgin; Tiemozyl; Cerfa 114; Cerfa-114; Cerfa114;

IUPAC/Chemical Name: 3-(4-Methylmorpholin-4-ium-4-yl)-1-phenyl-1-thiophen-2-ylpropan-1-ol iodide

InChi Key: IOFXEUZPIIUQAG-UHFFFAOYSA-M

InChi Code: InChI=1S/C18H24NO2S.HI/c1-19(11-13-21-14-12-19)10-9-18(20,17-8-5-15-22-17)16-6-3-2-4-7-16;/h2-8,15,20H,9-14H2,1H3;1H/q+1;/p-1

SMILES Code: OC(C1=CC=CS1)(C2=CC=CC=C2)CC[N+]3(C)CCOCC3.[I-]

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 445.35 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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19588914.


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8: Okada K, Imai H, Togawa Y, Nagaoka S, Nozaki M, Tsurumi K, Fujimura H. [Effect
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9: Gervais C, Lange P. [Visceralgine]. Soins. 1982 Jun;27(383):41-2. French.
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10: Tacke R, Zimonyi-Hegedüs E, Strecker M. [Sila-drugs, XX: Sila-analogue of
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Jun;313(6):515-26. German. PubMed PMID: 7406667.


11: Scoular IT, Monks A, Burgess C, Turner P. Human studies on the
bioavailability of a quaternary ammonium compounds, tiemonium iodide and
tiemonium methosulphate. Curr Med Res Opin. 1976-1977;4(10):732-8. PubMed PMID:
1052164.


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13: Pennefather JN, McCulloch MW, Czechowicz S, Pun LQ, Rush M, Rand MJ. Studies
with tiemonium iodide. An antispasmodic drug. Arch Int Pharmacodyn Ther. 1968
Jul;174(1):152-66. PubMed PMID: 4386710.


14: Beau G, Constantin M, Talvard J, Duchene-Marullaz P. [Elimination of
radioactive tiemonium iodide and research on its metabolites in rats and mice].
Therapie. 1968 Mar-Apr;23(2):399-409. French. PubMed PMID: 5701514.


15: Neveu J. [Tiemonium iodide-novamin sulfone combination in treatment of pain
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5634167.


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