Texaline

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 562005

CAS#: 115070-72-9

Description: Texaline is an antitubercular agent.

Chemical Structure

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Texaline
CAS# 115070-72-9
Instruction

Theoretical Analysis

MedKoo Cat#: 562005
Name: Texaline
CAS#: 115070-72-9
Chemical Formula: C15H10N2O3
Exact Mass: 266.07
Molecular Weight: 266.250
Elemental Analysis: C, 67.67; H, 3.79; N, 10.52; O, 18.03

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: Texaline; Texalin;

IUPAC/Chemical Name: 5-(Benzo[d][1,3]dioxol-5-yl)-2-(pyridin-3-yl)oxazole

InChi Key: SDHIXARCLVIOJM-UHFFFAOYSA-N

InChi Code: InChI=1S/C15H10N2O3/c1-2-11(7-16-5-1)15-17-8-14(20-15)10-3-4-12-13(6-10)19-9-18-12/h1-8H,9H2

SMILES Code: C1(C2=CC=CN=C2)=NC=C(C3=CC=C(OCO4)C4=C3)O1

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 266.25 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Chatterjee T, Cho JY, Cho EJ. Synthesis of Substituted Oxazoles by Visible-Light Photocatalysis. J Org Chem. 2016 Aug 19;81(16):6995-7000. doi: 10.1021/acs.joc.6b00989. Epub 2016 Jun 23. PubMed PMID: 27327044.

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4: Heuman AN, Scholl JC, Wilkinson K. Rural Hispanic populations at risk in developing diabetes: sociocultural and familial challenges in promoting a healthy diet. Health Commun. 2013;28(3):260-74. doi: 10.1080/10410236.2012.680947. Epub 2012 Jun 20. PubMed PMID: 22716086.

5: Yamamoto T, Muto K, Komiyama M, Canivet J, Yamaguchi J, Itami K. Nickel-catalyzed C-H arylation of azoles with haloarenes: scope, mechanism, and applications to the synthesis of bioactive molecules. Chemistry. 2011 Aug 29;17(36):10113-22. doi: 10.1002/chem.201101091. Epub 2011 Jul 8. PubMed PMID: 21744407.

6: Verrier C, Martin T, Hoarau C, Marsais F. Palladium-catalyzed direct (hetero)arylation of ethyl oxazole-4-carboxylate: an efficient access to (hetero)aryloxazoles. J Org Chem. 2008 Sep 19;73(18):7383-6. doi: 10.1021/jo801093n. Epub 2008 Aug 15. PubMed PMID: 18702548.

7: Besselièvre F, Mahuteau-Betzer F, Grierson DS, Piguel S. Ligandless microwave-assisted Pd/Cu-catalyzed direct arylation of oxazoles. J Org Chem. 2008 Apr 18;73(8):3278-80. doi: 10.1021/jo7027135. Epub 2008 Mar 19. PubMed PMID: 18348574.

8: Ohnmacht SA, Mamone P, Culshaw AJ, Greaney MF. Direct arylations on water: synthesis of 2,5-disubstituted oxazoles balsoxin and texaline. Chem Commun (Camb). 2008 Mar 14;(10):1241-3. doi: 10.1039/b719466h. Epub 2008 Feb 5. PubMed PMID: 18309430.