WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 571469

CAS#: 144398-20-9

Description: Acaterin is an inhibitor of acyl-CoA: cholesterol acyltransferase (ACAT). It inhibits synthesis of cholesteryl ester in macrophage J774.

Chemical Structure

CAS# 144398-20-9

Theoretical Analysis

MedKoo Cat#: 571469
Name: Acaterin
CAS#: 144398-20-9
Chemical Formula: C13H22O3
Exact Mass: 226.1569
Molecular Weight: 226.32
Elemental Analysis: C, 68.99; H, 9.80; O, 21.21

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: Acaterin

IUPAC/Chemical Name: 2(5H)-Furanone, 3-(1-hydroxyoctyl)-5-methyl-


InChi Code: InChI=1S/C13H22O3/c1-3-4-5-6-7-8-12(14)11-9-10(2)16-13(11)15/h9-10,12,14H,3-8H2,1-2H3


Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 226.32 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

Molarity Calculator

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1: Naganuma S, Sakai K, Hasumi K, Endo A. Acaterin, a novel inhibitor of acyl-CoA: cholesterol acyltransferase produced by Pseudomonas sp. A92. J Antibiot (Tokyo). 1992 Aug;45(8):1216-21. PubMed PMID: 1399841.

2: Nakano S, Sakane W, Oinaka H, Fujimoto Y. Biosynthesis of acaterin: mechanism of the reaction catalyzed by dehydroacaterin reductase. Bioorg Med Chem. 2006 Sep 15;14(18):6404-8. Epub 2006 Jun 9. PubMed PMID: 16765052.

3: Sekiyama Y, Fujimoto Y, Hasumi K, Endo A. Biosynthesis of acaterin: coupling of C(5) unit with octanoate. J Org Chem. 2001 Aug 24;66(17):5649-54. PubMed PMID: 11511235.

4: Hatano E, Hashidoko Y, Deora A, Fukushi Y, Tahara S. Isolation and structure elucidation of Peronosporomycetes hyphal branching-inducing factors produced by Pseudomonas jessenii EC-S101. Biosci Biotechnol Biochem. 2007 Jun;71(6):1601-5. PubMed PMID: 17587701.