WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 561098

CAS#: 432499-63-3

Description: 4E2RCat is an inhibitor of eIF4E-eIF4G interaction. 4E2RCat occupies four of the five “hot spots” present in the eIF4G/4E-BP binding region.

Price and Availability




4E2RCat is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 561098
Name: 4E2RCat
CAS#: 432499-63-3
Chemical Formula: C22H14ClNO4S2
Exact Mass: 455.0053
Molecular Weight: 455.93
Elemental Analysis: C, 57.96; H, 3.10; Cl, 7.78; N, 3.07; O, 14.04; S, 14.06

Synonym: 4E2R Cat; 4E2R-Cat; 4E2RCat

IUPAC/Chemical Name: 5-[5-[(E)-(3-Benzyl-4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene)methyl]furan-2-yl]-2-chlorobenzoic acid


InChi Code: InChI=1S/C22H14ClNO4S2/c23-17-8-6-14(10-16(17)21(26)27)18-9-7-15(28-18)11-19-20(25)24(22(29)30-19)12-13-4-2-1-3-5-13/h1-11H,12H2,(H,26,27)/b19-11+

SMILES Code: O=C(O)C1=CC(C2=CC=C(/C=C(SC(N3CC4=CC=CC=C4)=S)\C3=O)O2)=CC=C1Cl

Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:


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