WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 530601

CAS#: 959551-10-1

Description: NIH-12848 is a putative phosphatidylinositol 5-phosphate 4-kinase γ (PI5P4Kγ) inhibitor. NIH-12848 inhibited PI5P4Kγ with an IC50 of approximately 1 μM but did not inhibit the α and β PI5P4K isoforms at concentrations up to 100 μM. NIH-12848 is a potentially powerful tool for exploring the cell physiology of PI5P4Ks.

Price and Availability

Size Price Shipping out time Quantity
100mg USD 850 2 Weeks
200mg USD 1250 2 Weeks
500mg USD 2150 2 Weeks
1g USD 3450 2 Weeks
2g USD 4250 2 Weeks
5g USD 6450 2 Weeks
Inquire bulk and customized quantity

Pricing updated 2021-01-18. Prices are subject to change without notice.

NIH-12848, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 530601
Name: NIH-12848
CAS#: 959551-10-1
Chemical Formula: C20H14F3N3S
Exact Mass: 385.0861
Molecular Weight: 385.4082
Elemental Analysis: C, 62.33; H, 3.66; F, 14.79; N, 10.90; S, 8.32

Synonym: NIH-12848; NIH 12848; NIH12848, NCGC00012848-02.

IUPAC/Chemical Name: N-(thiophen-2-ylmethyl)-2-(2-(trifluoromethyl)phenyl)quinazolin-4-amine


InChi Code: InChI=1S/C20H14F3N3S/c21-20(22,23)16-9-3-1-7-14(16)19-25-17-10-4-2-8-15(17)18(26-19)24-12-13-6-5-11-27-13/h1-11H,12H2,(H,24,25,26)


Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


1: Clarke JH, Giudici ML, Burke JE, Williams RL, Maloney DJ, Marugan J, Irvine
RF. The function of phosphatidylinositol 5-phosphate 4-kinase γ (PI5P4Kγ)
explored using a specific inhibitor that targets the PI5P-binding site. Biochem
J. 2015 Mar 1;466(2):359-67. doi: 10.1042/BJ20141333. PubMed PMID: 25495341;
PubMed Central PMCID: PMC4687057.