UK-9040

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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 526534

CAS#: 47453-14-5

Description: UK-9040 is a gastric secretory inhibitor.


Price and Availability

Size Price Shipping out time Quantity
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Pricing updated 2020-10-29. Prices are subject to change without notice.

UK-9040 is not in stock, but may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 526534
Name: UK-9040
CAS#: 47453-14-5
Chemical Formula: C23H31NS
Exact Mass: 353.2177
Molecular Weight: 353.568
Elemental Analysis: C, 78.13; H, 8.84; N, 3.96; S, 9.07


Synonym: UK-9040, UK 9040, UK9040

IUPAC/Chemical Name: Pyrrolidine, 1-(4-(5-(2,2-dimethylpropyl)-2-thienyl)-4-phenyl-3-butenyl)-, (Z)-

InChi Key: HZZXGWBOCXDVLV-MTJSOVHGSA-N

InChi Code: InChI=1S/C23H31NS/c1-23(2,3)18-20-13-14-22(25-20)21(19-10-5-4-6-11-19)12-9-17-24-15-7-8-16-24/h4-6,10-14H,7-9,15-18H2,1-3H3/b21-12-

SMILES Code: CC(C)(C)CC1=CC=C(/C(C2=CC=CC=C2)=C\CCN3CCCC3)S1


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.9001


References

1: Hamer DB, Price AB, Baron JH. Morphological and pharmacological studies of the parietal cells of the stomach in the dog during periods of maximal acid output and after the gastric secretory inhibitor UK-9040. Gut. 1977 Feb;18(2):91-8. PubMed PMID: 852749; PubMed Central PMCID: PMC1411295.

2: Joffe SN, Polak JM, Pallone F, Bloom SR, Gaskin RJ, Barros D'sa AA, Baron JH. Gastrin, antral g cells, and gastric acid in secretagogue-induced and antihistamine-inhibited duodenal ulcers. Scand J Gastroenterol. 1977;12(1):27-32. PubMed PMID: 13481.

3: Joffe SN, Gaskin RJ, D'Sa AA. Prevention of secretagogue-induced ulcers in the rat. Gastroenterology. 1976 May;70(5 PT.1):751-2. PubMed PMID: 1261768.

4: Joffe SN, Gaskin R, Barros D'sa AA, Melo AA, Gribble JN, Girvan DP, Baron JH. Proceedings: Secretagogue-produced duodenal ulcers in the rat and their prevention by the gastric secretory inhibitor UK 9040. Br J Surg. 1975 Feb;62(2):157. PubMed PMID: 234768.

5: Hamer DB, Price AB, Baron JH. Proceedings: A morphological and pharmacological study of the parietal cells of the stomach in the dog during periods of maximal acid output and after the gastric secretory inhibitor UK-9040. Gut. 1974 Apr;15(4):336-7. PubMed PMID: 4151863.

6: Hamer DB, Baron JH, Spencer J. Studies with a new gastric secretory inhibitor (UK 9040) in the dog. Br J Surg. 1972 Nov;59(11):902. PubMed PMID: 4637105.